104 T3 at University Of Brighton | Flashcards & Summaries

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Lernmaterialien für 104 T3 an der University of Brighton

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TESTE DEIN WISSEN

What are some of the functions of the kidney?

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-> Excretion of endogenous waste products

-> Excretion of drugs and their metabolites

-> Water and electrolyte balance

-> Acid-base balance

-> Production of hormones, e.g. erythropoietin, renin

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TESTE DEIN WISSEN

When might renal tubular acidosis occur?

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If the kidneys cannot reabsorb HCO3- and secrete H+ properly eg in renal failure

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What is the role of the kidney in controlling acid base balance?

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H+ ion concentration is monitored

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What are some features of renal dysfunction?

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-> Reduction in renal excretory function (uraemia)

-> Reduction in renal excretory function (drug toxicity)

-> Inability to maintain salt and water balance and acid-base balance (metabolic consequences)

-> Hormone function reduced (anaemia, hypertension, etc)

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TESTE DEIN WISSEN

What is the role of the kidney in volume regulation?

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It maintains fluid and electrolyte balance

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What is the name of the condition where plasma pH levels fall below 7.35?

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Acidosis

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What is the name of the condition where plasma pH levels are above 7.45?

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TESTE DEIN WISSEN

Alkalosis

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What does an alteration outside healthy pH range result in?

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TESTE DEIN WISSEN

Coma, cardiac failure and circulatory collapse 

At pH < 6.8 or > 8 death occurs

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TESTE DEIN WISSEN

What are the main types of buffer systems in the body?

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- Carbonic acid/bicarbonate

- Protein 

- Phosphate

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TESTE DEIN WISSEN

The renal system integrates with the respiratory and cardiovascular systems to maintain ________

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TESTE DEIN WISSEN

Homeostasis

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TESTE DEIN WISSEN

What is the normal range of pH of the ECF (extracellular fluid)?

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TESTE DEIN WISSEN

7.35 and 7.45

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TESTE DEIN WISSEN

How is metabolic acidosis treated?

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TESTE DEIN WISSEN

IV isotonic HCO3- should be given

IV lactate solution should be given (Ringer's lactate or Hartmann's solution) -> converted to HCO3- buffer in liver

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Q:

What are some of the functions of the kidney?

A:

-> Excretion of endogenous waste products

-> Excretion of drugs and their metabolites

-> Water and electrolyte balance

-> Acid-base balance

-> Production of hormones, e.g. erythropoietin, renin

Q:

When might renal tubular acidosis occur?

A:

If the kidneys cannot reabsorb HCO3- and secrete H+ properly eg in renal failure

Q:

What is the role of the kidney in controlling acid base balance?

A:

H+ ion concentration is monitored

Q:

What are some features of renal dysfunction?

A:

-> Reduction in renal excretory function (uraemia)

-> Reduction in renal excretory function (drug toxicity)

-> Inability to maintain salt and water balance and acid-base balance (metabolic consequences)

-> Hormone function reduced (anaemia, hypertension, etc)

Q:

What is the role of the kidney in volume regulation?

A:

It maintains fluid and electrolyte balance

Mehr Karteikarten anzeigen
Q:

What is the name of the condition where plasma pH levels fall below 7.35?

A:

Acidosis

Q:

What is the name of the condition where plasma pH levels are above 7.45?

A:

Alkalosis

Q:

What does an alteration outside healthy pH range result in?

A:

Coma, cardiac failure and circulatory collapse 

At pH < 6.8 or > 8 death occurs

Q:

What are the main types of buffer systems in the body?

A:

- Carbonic acid/bicarbonate

- Protein 

- Phosphate

Q:

The renal system integrates with the respiratory and cardiovascular systems to maintain ________

A:

Homeostasis

Q:

What is the normal range of pH of the ECF (extracellular fluid)?

A:

7.35 and 7.45

Q:

How is metabolic acidosis treated?

A:

IV isotonic HCO3- should be given

IV lactate solution should be given (Ringer's lactate or Hartmann's solution) -> converted to HCO3- buffer in liver

104 T3

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