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Lernmaterialien für MICROBIOLOGY an der Universiti Sultan Zainal Abidin

Greife auf kostenlose Karteikarten, Zusammenfassungen, Übungsaufgaben und Altklausuren für deinen MICROBIOLOGY Kurs an der Universiti Sultan Zainal Abidin zu.

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Complications of pertussis?

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  • Pneumonia – most common, bacteria invade tissues
  • Seizures & encephalopathy (a diffuse disorder of the brain) due to hypoxia from coughing, or possibly from toxin.
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Explain cutaneous diphtheria

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  • Skin infections may be manifested by a scaling rash or by ulcers with clearly demarcated edges and pseudomembrane


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​Give investigation and diagnosis for epiglottitis

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  • Fiberoptic laryngoscopy - classic swollen,
    cherry red epiglottis
  • Lateral neck xray – enlarged edematous
    epiglottis (“thumb sign”)
  • WBC – mild to moderate leucocytosis with
    predominance of neutrophil
  • Blood C&S- positive in significant proportion of
    cases
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Define  croup, pertussis and diphteria

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  • Croup= Laryngotracheobronchitis
  • Pertussis= Tracheobronchitis (whooping cough)
  • Diphtheria= Pharyngeal & laryngeal diphtheria
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Give diagnostic clues for HSV & coxsackievirus

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Presence of vesicles and ulcers. Coxsackievirus-related vesicles often occur on the hard palate

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Complications of diphtheriae?

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  • Myocarditis
  • Neuritis
  • Thrombocytopenia
  • Proteinuria
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Patients have fever, tonsillar swelling, pharyngeal exudate, painful & difficulty in swallowing, enlarged/ tender anterior cervical lymph nodes & absence of cough or coryza. Suggest the aetiology.

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Streptococcus pyogenes pharyngitis

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​What is common causative organism in epiglottitis?

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  1. HIB
  2. Streptococcus pyogenes
  3. Streptococcal pneumonia
  4. Haemophilus parainfluenza
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Give the medication for epiglottitis

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  • Antibiotic therapy
  • Empiric antimicrobial therapy must cover all likely pathogens
  • Combination of β-lactam/β-lactamase inhibitor e.g
    ampicillin/sulbactam
  • third generation cephalosporins –cefuroxime, cefotaxime, ceftriaxone
  • Clindamycin and TMP-SMX – reserved for pts allergic to β-lactams
  • Sedation for comfort
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Prognosis of epigottitis?

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Once the airway has been secured, prognosis is excellent, with the mortality rate falling below 1%.

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Epiglottitis usually affects who?

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Young children than 5 years but can occur in older patients

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What test should do for toxigenecity

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ELISA or ELEK test

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  • 1314 Karteikarten
  • 101 Studierende
  • 1 Lernmaterialien

Beispielhafte Karteikarten für deinen MICROBIOLOGY Kurs an der Universiti Sultan Zainal Abidin - von Kommilitonen auf StudySmarter erstellt!

Q:

Complications of pertussis?

A:
  • Pneumonia – most common, bacteria invade tissues
  • Seizures & encephalopathy (a diffuse disorder of the brain) due to hypoxia from coughing, or possibly from toxin.
Q:

Explain cutaneous diphtheria

A:
  • Skin infections may be manifested by a scaling rash or by ulcers with clearly demarcated edges and pseudomembrane


Q:

​Give investigation and diagnosis for epiglottitis

A:
  • Fiberoptic laryngoscopy - classic swollen,
    cherry red epiglottis
  • Lateral neck xray – enlarged edematous
    epiglottis (“thumb sign”)
  • WBC – mild to moderate leucocytosis with
    predominance of neutrophil
  • Blood C&S- positive in significant proportion of
    cases
Q:

Define  croup, pertussis and diphteria

A:
  • Croup= Laryngotracheobronchitis
  • Pertussis= Tracheobronchitis (whooping cough)
  • Diphtheria= Pharyngeal & laryngeal diphtheria
Q:

Give diagnostic clues for HSV & coxsackievirus

A:

Presence of vesicles and ulcers. Coxsackievirus-related vesicles often occur on the hard palate

Mehr Karteikarten anzeigen
Q:

Complications of diphtheriae?

A:
  • Myocarditis
  • Neuritis
  • Thrombocytopenia
  • Proteinuria
Q:

Patients have fever, tonsillar swelling, pharyngeal exudate, painful & difficulty in swallowing, enlarged/ tender anterior cervical lymph nodes & absence of cough or coryza. Suggest the aetiology.

A:

Streptococcus pyogenes pharyngitis

Q:

​What is common causative organism in epiglottitis?

A:
  1. HIB
  2. Streptococcus pyogenes
  3. Streptococcal pneumonia
  4. Haemophilus parainfluenza
Q:

Give the medication for epiglottitis

A:
  • Antibiotic therapy
  • Empiric antimicrobial therapy must cover all likely pathogens
  • Combination of β-lactam/β-lactamase inhibitor e.g
    ampicillin/sulbactam
  • third generation cephalosporins –cefuroxime, cefotaxime, ceftriaxone
  • Clindamycin and TMP-SMX – reserved for pts allergic to β-lactams
  • Sedation for comfort
Q:

Prognosis of epigottitis?

A:

Once the airway has been secured, prognosis is excellent, with the mortality rate falling below 1%.

Q:

Epiglottitis usually affects who?

A:

Young children than 5 years but can occur in older patients

Q:

What test should do for toxigenecity

A:

ELISA or ELEK test

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