Physiologie at Universität Leipzig

Flashcards and summaries for Physiologie at the Universität Leipzig

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Exemplary flashcards for Physiologie at the Universität Leipzig on StudySmarter:

Glucocorticoide: Wirkungen auf Bindegewebe, Knochen, Ca-Stoffwechsel

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Wo wird Aldosteron gebildet? 

Exemplary flashcards for Physiologie at the Universität Leipzig on StudySmarter:

Was wird in der Zona fasciculata der NNR gebildet? 

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Exemplary flashcards for Physiologie at the Universität Leipzig on StudySmarter:

Wie steht Albumin zu Cortisol? 

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Wofür benötigen wir Ribose-5-Phosphat?

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Nenne eine Quelle für NADPH (Enzym des Pentosephosphatwegs)

Exemplary flashcards for Physiologie at the Universität Leipzig on StudySmarter:

2. Sekundärer Hyperaldosteronismus
(Aldosteronüberproduktion mit Aktivierung des RAS)


Pathogenese

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Exemplary flashcards for Physiologie at the Universität Leipzig on StudySmarter:

Was zählt zu den Sexualhormonen der NNR?

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Wo wird CBG produziert? 

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Welches Enzym macht als Colesterol Pregnenolon?

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Was zählt zu den Glucocorticoiden? 

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Was wird in der Zona Glomerulosa der NNR gebildet?

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Exemplary flashcards for Physiologie at the Universität Leipzig on StudySmarter:

Physiologie

Glucocorticoide: Wirkungen auf Bindegewebe, Knochen, Ca-Stoffwechsel

→ Hemmung der Fibroblasten → Kollagen / Bindegewebe ↓
→ Knochenaufbau ↓ (Osteolyse ↑ )
→ intestinale Ca-Absorption ↓
→ renale Ca- und P-Ausscheidung ↑

Physiologie

Wo wird Aldosteron gebildet? 

Zona glomerulosa der NNR

Physiologie

Was wird in der Zona fasciculata der NNR gebildet? 

Glucokortikoide

Physiologie

Wie steht Albumin zu Cortisol? 

  • Albumin
    schwache Affinität zu Cortisol
  • hohe Affinität zu synthetischen
    Glucocorticosteroiden (Dexamethason)

Physiologie

Wofür benötigen wir Ribose-5-Phosphat?

zur Synthese von Nucleotiden (Stoffwelchsel, DNA-, RNA-Synthese)

Physiologie

Nenne eine Quelle für NADPH (Enzym des Pentosephosphatwegs)

Glucose-6-P-Dehydrogenase

Physiologie

2. Sekundärer Hyperaldosteronismus
(Aldosteronüberproduktion mit Aktivierung des RAS)


Pathogenese

• renale Na+-Ausscheidung ↓
• Herzinsuffizienz
• chronisches Nierenversagen
• Leberzirrhose

Physiologie

Was zählt zu den Sexualhormonen der NNR?

DHEA, Androstendion

Physiologie

Wo wird CBG produziert? 

In der Leber (CBG = 

Corticosteroid-Binding Globulin, = Transcortin)

Physiologie

Welches Enzym macht als Colesterol Pregnenolon?

Cholesteroldesmolase

Physiologie

Was zählt zu den Glucocorticoiden? 

Cortisol, Corticosteron

Physiologie

Was wird in der Zona Glomerulosa der NNR gebildet?

Mineralokortikoide

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