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Which cancer has the highest incidence in men?

prostata cancer

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Which cancer has the highest mortality in men?

lung and bronchus cancer

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Women can get cancer of the urinary tract as well. Which cancer has the highest incidence (percentage?)

kidnes and renal pelvis, 3%

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Which of the renal cell carcinoma subtypes is most frequent?

clear cell RCC with 75%

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Which copy number alterations are characteristic for clear cell renal carcinoma?

loss of chromosome 3p (91%)

gain of chromosome 5q

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Name the four frequently mutated genes in clear cell renal carcinoma. On which chromome are they?

VHL

PBRM1

SETD2

BAP1

on chromosome 3p

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p53 is frequently mutated in clear cell renal carcinoma

false

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treatment of clear cell renal carcinoma in an early stage

surgery is th only curative option

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treatment of clear cell renal carcinoma in an late stage

usually targeted therapy

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How is clear cell renal carcinoma currently treated?

combination of tyrosine kinase inhibitors with immune checkpoint inhibitors

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CTLA4

is on the surface of T cells

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PD1 is on the surface of

T cells

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Disease affected organism at Universität Göttingen

Flashcards and summaries for Disease affected organism at the Universität Göttingen

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Disease affected organism at Universität Göttingen

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