Disease affected organism at Universität Göttingen

Flashcards and summaries for Disease affected organism at the Universität Göttingen

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Which cancer has the highest incidence in men?

Exemplary flashcards for Disease affected organism at the Universität Göttingen on StudySmarter:

Which cancer has the highest mortality in men?

Exemplary flashcards for Disease affected organism at the Universität Göttingen on StudySmarter:

Women can get cancer of the urinary tract as well. Which cancer has the highest incidence (percentage?)

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Exemplary flashcards for Disease affected organism at the Universität Göttingen on StudySmarter:

Which of the renal cell carcinoma subtypes is most frequent?

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Which copy number alterations are characteristic for clear cell renal carcinoma?

Exemplary flashcards for Disease affected organism at the Universität Göttingen on StudySmarter:

Name the four frequently mutated genes in clear cell renal carcinoma. On which chromome are they?

Exemplary flashcards for Disease affected organism at the Universität Göttingen on StudySmarter:

p53 is frequently mutated in clear cell renal carcinoma

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treatment of clear cell renal carcinoma in an early stage

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treatment of clear cell renal carcinoma in an late stage

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How is clear cell renal carcinoma currently treated?

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CTLA4

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PD1 is on the surface of

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Exemplary flashcards for Disease affected organism at the Universität Göttingen on StudySmarter:

Disease affected organism

Which cancer has the highest incidence in men?

prostata cancer

Disease affected organism

Which cancer has the highest mortality in men?

lung and bronchus cancer

Disease affected organism

Women can get cancer of the urinary tract as well. Which cancer has the highest incidence (percentage?)

kidnes and renal pelvis, 3%

Disease affected organism

Which of the renal cell carcinoma subtypes is most frequent?

clear cell RCC with 75%

Disease affected organism

Which copy number alterations are characteristic for clear cell renal carcinoma?

loss of chromosome 3p (91%)

gain of chromosome 5q

Disease affected organism

Name the four frequently mutated genes in clear cell renal carcinoma. On which chromome are they?

VHL

PBRM1

SETD2

BAP1

on chromosome 3p

Disease affected organism

p53 is frequently mutated in clear cell renal carcinoma

false

Disease affected organism

treatment of clear cell renal carcinoma in an early stage

surgery is th only curative option

Disease affected organism

treatment of clear cell renal carcinoma in an late stage

usually targeted therapy

Disease affected organism

How is clear cell renal carcinoma currently treated?

combination of tyrosine kinase inhibitors with immune checkpoint inhibitors

Disease affected organism

CTLA4

is on the surface of T cells

Disease affected organism

PD1 is on the surface of

T cells

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Paper Diskussion

Französisch

Cardio and Pharma

Organisation at

Bergische Universität Wuppertal

Organisation at

Duale Hochschule Baden-Württemberg

Organisation at

Hochschule Bochum

Organische at

Hochschule für Angewandte Wissenschaften Hamburg

Organisation at

International School of Management

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