hyperlipidämie at RWTH Aachen

Flashcards and summaries for hyperlipidämie at the RWTH Aachen

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Exemplary flashcards for hyperlipidämie at the RWTH Aachen on StudySmarter:

Metabolisches Syndrom

Exemplary flashcards for hyperlipidämie at the RWTH Aachen on StudySmarter:

wichtigste und gefährlichste Formen der genetischen Hyperlipidämien

Exemplary flashcards for hyperlipidämie at the RWTH Aachen on StudySmarter:

Therapierichtlinien der European Atherosclerosis Society bei Hyperlipidämiw
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Exemplary flashcards for hyperlipidämie at the RWTH Aachen on StudySmarter:

Mäßiger schweregrad

Exemplary flashcards for hyperlipidämie at the RWTH Aachen on StudySmarter:

Schwere Hyperlipidämie 

Exemplary flashcards for hyperlipidämie at the RWTH Aachen on StudySmarter:

Angriffspunkte bei Hyperlipidämie 

Exemplary flashcards for hyperlipidämie at the RWTH Aachen on StudySmarter:

Unterbrechung des enterohepatisches kreislaufs
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Exemplary flashcards for hyperlipidämie at the RWTH Aachen on StudySmarter:

Wirkmechanismus Colestyramin, Colestipol, Colesavelam

Exemplary flashcards for hyperlipidämie at the RWTH Aachen on StudySmarter:

Wirkung Colestyramin

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UAW Colestyramin, Colestipol, Colesavelam 

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KI Colestyramin, Colestipol, Colesavelam
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Hemmung der Resorption im Darm

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Exemplary flashcards for hyperlipidämie at the RWTH Aachen on StudySmarter:

hyperlipidämie

Metabolisches Syndrom

-abdominelle Fettleibligkeit,
-Dyslipidämie,
-Hypertonie,
-Insulinresistenz

=> entscheidender Faktor für KHK

hyperlipidämie

wichtigste und gefährlichste Formen der genetischen Hyperlipidämien
 => gemischte, familiäre Hypercholesterinämie
→ LDL ↑ → KHK‐Risiko ++++

=> Hyperlipidämie
→ VLDL, LDL ↑ → KHK‐Risiko +++


hyperlipidämie

Therapierichtlinien der European Atherosclerosis Society bei Hyperlipidämiw
mäßige Hyperlipidämie wird nur mit Fibraten & Nikotinsäure behandelt bei
-Diätversagern
-KHK mit low HDL
-hohem Allgrisiko

hyperlipidämie

Mäßiger schweregrad
Triglyceride 200‐400mg/dl
LDL‐Cholesterin<135mg/dl

hyperlipidämie

Schwere Hyperlipidämie 
Triglyceride>400mg/dl
LDL‐Cholesterin>175mg/dl

hyperlipidämie

Angriffspunkte bei Hyperlipidämie 
-Unterbrechung des enterohepatischen kreislaufs
-hemmung der HMG-CoA-Synthetase
-Hemmung der resorption im darm
-Hemmung der lipoproteins

hyperlipidämie

Unterbrechung des enterohepatisches kreislaufs
Anionenaustauscherharze

Colestyramin
Colestipol
Colesavelam

hyperlipidämie

Wirkmechanismus Colestyramin, Colestipol, Colesavelam
Anionenaustauschharze
 saure Gallensäuren werden durch Ionenaustauscher gebunden dadurch Störung des enterohepatischen Rücktransports

hyperlipidämie

Wirkung Colestyramin
durch Stimulation des LDL‐Rezeptor, Steigerung des LDL‐Abbaus

hyperlipidämie

UAW Colestyramin, Colestipol, Colesavelam 
Sodbrennen
Übelkeit
Obstipation
Anorexie
Meteorismus

hyperlipidämie

KI Colestyramin, Colestipol, Colesavelam
Pat mit zusätzlicher Triglyzeridämie

hyperlipidämie

Hemmung der Resorption im Darm
Ezetimib

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