Immunology - Immunity to Bacteria at Hochschule Bonn-Rhein-Sieg

Flashcards and summaries for Immunology - Immunity to Bacteria at the Hochschule Bonn-Rhein-Sieg

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Exemplary flashcards for Immunology - Immunity to Bacteria at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

How many types of Responses against pathogens are known? In how many categories are they divided? 

Exemplary flashcards for Immunology - Immunity to Bacteria at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is the trigger for Type 1 response?

Exemplary flashcards for Immunology - Immunity to Bacteria at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is involved in Type 1 response?
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What is the trigger for Type 2 response?

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What is involved in Type 2 response?

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What is the trigger for Type 3 response?

Exemplary flashcards for Immunology - Immunity to Bacteria at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is involved in Type 3 response?
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Exemplary flashcards for Immunology - Immunity to Bacteria at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is the first barrier which has to be overcome (extracellular pathogens)?

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What is involved in physical barriers?

Exemplary flashcards for Immunology - Immunity to Bacteria at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is the function of lysosyme?

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What is the function of defensins and what are they?
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What is the second line defense?

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Exemplary flashcards for Immunology - Immunity to Bacteria at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Immunology - Immunity to Bacteria

How many types of Responses against pathogens are known? In how many categories are they divided? 
3

Immunology - Immunity to Bacteria

What is the trigger for Type 1 response?
- intracellular pathogens (intracellular bacteria/viruses)

Immunology - Immunity to Bacteria

What is involved in Type 1 response?
TH-1
CTL
NK-Cells
ILC-1
IFN-gamma

Immunology - Immunity to Bacteria

What is the trigger for Type 2 response?
Parasites

Immunology - Immunity to Bacteria

What is involved in Type 2 response?
Granulocytes
Mast cells
TH2
ILC2

Immunology - Immunity to Bacteria

What is the trigger for Type 3 response?
Extracellular pathogens (such as bacteria/fungi)

Immunology - Immunity to Bacteria

What is involved in Type 3 response?
TH17
Neutrophils
Phagocytotic cells
IL-17
IL-22

Immunology - Immunity to Bacteria

What is the first barrier which has to be overcome (extracellular pathogens)?
Anatomic barrier which are:
Physical and chemical barriers

Immunology - Immunity to Bacteria

What is involved in physical barriers?
Tight junctions
Microbiome
Low pH (stomach)
(Air) flow (on skin)
Mucous flow in airways
Flow in the gut

Immunology - Immunity to Bacteria

What is the function of lysosyme?
Cleavage of cell wall peptidoglycans

Immunology - Immunity to Bacteria

What is the function of defensins and what are they?
  • Integration due to their charge and form pores
  • cationic anit-microbial peptides

Immunology - Immunity to Bacteria

What is the second line defense?
Complement system

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