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DB Chapter 6: Fertilization
What happens in fertilization generally?
Sperm and egg (gametes) fuse to form a zygote whose genome is derived from both parents.
DB Chapter 6: Fertilization
What is the requirement of gametes for fertilization?
They have to reduce their genetic material by half: from diploid to haploid.
DB Chapter 6: Fertilization
What is the process called, where diploid cells become haploid?
Meiosis
DB Chapter 6: Fertilization
Meiosis is the process by which one diploid eukaryotic cell devides to generate ____ haploid cells.
4
DB Chapter 6: Fertilization
What leads to DNA rearrangement in meiosis?
DB Chapter 6: Fertilization
At the time of fertilization, the egg has a __________ pronucleus.
haploid
DB Chapter 6: Fertilization
What is the zona pellucida?
A glycoprotein matrix that surround the egg.
DB Chapter 6: Fertilization
The binding of sperms to the zona pellucida has some species-specificity.
Right.
DB Chapter 6: Fertilization
Which kind of enzymes do acrosomal enzymes mainly consist of?
Mainly proteases.
DB Chapter 6: Fertilization
What is the difference between the egg and sperm fusion of sea urchins and mammals?
Sea urchin sperm binds to the microvilli of the egg with the acrosomal process, while sperm of mammals bind with the equatorial domain.
Both are then fused and internalised.
DB Chapter 6: Fertilization
At the time of fertilization the egg is arrested in the __________ of the second mitotic division.
Metaphase
DB Chapter 6: Fertilization
What leads to completion of meiosis and formation of the female pronucleus?
Calcium waves
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