CM - Karteikarten at Hochschule Bonn-Rhein-Sieg

Flashcards and summaries for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg

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Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are the 4 steps of cell migration? 

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Which kind of protrusions are there? 

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are characteristic features of haptotactic molecules?

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is the function of Cdc42 during cell migration? 

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Which kind of cell migration mechanisms are there? 

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are the functions of PAR3 and PAR6

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Which molecules are associated with traction and adhesion

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Give examples for non-neoplastic examples of collective cell migration!

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Which molecule is essential for collective cell migration?

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are advantages of scratch/wound healing assay

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are disadvantages of scratch/wound healing assay?

Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

In which kind of specific cell migration are cadherins important? 

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Exemplary flashcards for CM - Karteikarten at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

CM - Karteikarten

What are the 4 steps of cell migration? 

1. Cell polarization 

2. Protrusion

3. Traction

4. Retraction 

CM - Karteikarten

Which kind of protrusions are there? 

1. Filopodia

(long thin protrusion emerging from cell membrane) 


2. Lamellipodia

(thick, sheetlike protrusion with branched network of actin filaments) 


3. Stress fibers

(thick bundle of actin fibres with myosin II and contraction ability) 


4. Arcs

(thick big bundles of actin fibres for structural support) 

CM - Karteikarten

What are characteristic features of haptotactic molecules?

  • surface bound
  • chemoattractive 
  • supports directed cell migration

CM - Karteikarten

What is the function of Cdc42 during cell migration? 

  • Formation of actin rich structures (e.g. filopodia) 
  • Polarization of cell 
  • Reorganisation of golgi apparatus

CM - Karteikarten

Which kind of cell migration mechanisms are there? 

  • Single cell migrations (amoeboid, mesenchymal) 
  • Collective cell migration 

CM - Karteikarten

What are the functions of PAR3 and PAR6

  • regulator for asymmetric cell division and polarized growth
  • spine morphogenesis

CM - Karteikarten

Which molecules are associated with traction and adhesion

  • Integrin
  • Tensin
  • Talin
  • FAK

CM - Karteikarten

Give examples for non-neoplastic examples of collective cell migration!

  • budding epithelial ducts
  • glands

CM - Karteikarten

Which molecule is essential for collective cell migration?

  • Adhesion & communication molecules (Cadherins, gap junctions) 

CM - Karteikarten

What are advantages of scratch/wound healing assay

  • easy to handle/get data
  • cheap microscope

CM - Karteikarten

What are disadvantages of scratch/wound healing assay?

  • destroys ECM
  • artificial border
  • difference between single & collective migration 

CM - Karteikarten

In which kind of specific cell migration are cadherins important? 

Collective cell migration 

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