Antithrombotic Drugs at Gaziantep University | Flashcards & Summaries

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TESTE DEIN WISSEN

47-year-old woman presents to the emergency room with severe bleeding. Upon evaluation of the  medical record, you discover that she takes dabigatran for a history of multiple deep vein thrombosis. What  is the appropriate reversal agent to administer to the patient at this time?


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idarucizumab

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Which of the following drug is approved as an adjunct during  percutaneous coronary intervention (PCI) to reduce thrombotic events in select patients?

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Cangrelor

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TESTE DEIN WISSEN

Which of the following drug carries a black box warning for diminished  effectiveness with concomitant use of aspirin doses above 100  mg?

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TESTE DEIN WISSEN

Ticagrelor

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TESTE DEIN WISSEN

Which of the following is used for the prophylaxis or treatment of venous  thromboembolism in patients with heparin-induced  thrombocytopenia (HIT), and it is also approved for use during  percutaneous coronary intervention (PCI) in patients who  have or are at risk for developing HIT?


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Argatroban

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Which of the following drug is a recombinant modified factor Xa protein  approved by the FDA in May 2018 for the reversal of apixaban  and rivaroxaban in patients with life-threatening or  uncontrolled bleeding?


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TESTE DEIN WISSEN

Andexanet alfa

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TESTE DEIN WISSEN

Which of the following drug is a synthetically derived  pentasaccharide anticoagulant that selectively inhibits factor  Xa. By selectively binding to antithrombin III, fondaparinux  potentiates (300- to 1000-fold) the innate neutralization of  factor Xa by antithrombin III and approved for use in the treatment of deep vein  thrombosis (DVT) and pulmonary embolism (PE), and for the  prophylaxis of venous thromboembolism in the setting of  orthopedic and abdominal surgery.


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TESTE DEIN WISSEN

Fondaparinux

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TESTE DEIN WISSEN

Which of the following drugs is an oral direct thrombin inhibitor and is used or the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation?


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TESTE DEIN WISSEN

Dabigatran

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TESTE DEIN WISSEN

Which is most appropriate for reversing the anticoagulant effects of heparin?

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TESTE DEIN WISSEN

protamine sulfate

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TESTE DEIN WISSEN

Concerning anticoagulants, all of the following are correct except


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TESTE DEIN WISSEN

Warfarin is the preferred anticoagulant in pregnant women

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TESTE DEIN WISSEN

Which of the following anti-platelet durg (a humanized monoclonal antibody) is glycoprotein IIb/IIIa and vitronectin receptor antagonist?


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TESTE DEIN WISSEN

Abcimixab

Lösung ausblenden
TESTE DEIN WISSEN

Which of the P2Y12 ADP receptor antagonists reversibly binds the receptor?


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TESTE DEIN WISSEN

Ticagrelor

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TESTE DEIN WISSEN

Which must heparin bind to in order to exert its anticoagulant effect?

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TESTE DEIN WISSEN

Antithrombin III

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Q:

47-year-old woman presents to the emergency room with severe bleeding. Upon evaluation of the  medical record, you discover that she takes dabigatran for a history of multiple deep vein thrombosis. What  is the appropriate reversal agent to administer to the patient at this time?


A:

idarucizumab

Q:

Which of the following drug is approved as an adjunct during  percutaneous coronary intervention (PCI) to reduce thrombotic events in select patients?

A:

Cangrelor

Q:

Which of the following drug carries a black box warning for diminished  effectiveness with concomitant use of aspirin doses above 100  mg?

A:

Ticagrelor

Q:

Which of the following is used for the prophylaxis or treatment of venous  thromboembolism in patients with heparin-induced  thrombocytopenia (HIT), and it is also approved for use during  percutaneous coronary intervention (PCI) in patients who  have or are at risk for developing HIT?


A:

Argatroban

Q:

Which of the following drug is a recombinant modified factor Xa protein  approved by the FDA in May 2018 for the reversal of apixaban  and rivaroxaban in patients with life-threatening or  uncontrolled bleeding?


A:

Andexanet alfa

Mehr Karteikarten anzeigen
Q:

Which of the following drug is a synthetically derived  pentasaccharide anticoagulant that selectively inhibits factor  Xa. By selectively binding to antithrombin III, fondaparinux  potentiates (300- to 1000-fold) the innate neutralization of  factor Xa by antithrombin III and approved for use in the treatment of deep vein  thrombosis (DVT) and pulmonary embolism (PE), and for the  prophylaxis of venous thromboembolism in the setting of  orthopedic and abdominal surgery.


A:

Fondaparinux

Q:

Which of the following drugs is an oral direct thrombin inhibitor and is used or the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation?


A:

Dabigatran

Q:

Which is most appropriate for reversing the anticoagulant effects of heparin?

A:

protamine sulfate

Q:

Concerning anticoagulants, all of the following are correct except


A:

Warfarin is the preferred anticoagulant in pregnant women

Q:

Which of the following anti-platelet durg (a humanized monoclonal antibody) is glycoprotein IIb/IIIa and vitronectin receptor antagonist?


A:

Abcimixab

Q:

Which of the P2Y12 ADP receptor antagonists reversibly binds the receptor?


A:

Ticagrelor

Q:

Which must heparin bind to in order to exert its anticoagulant effect?

A:

Antithrombin III

Antithrombotic Drugs

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