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47-year-old woman presents to the emergency room with severe bleeding. Upon evaluation of the medical record, you discover that she takes dabigatran for a history of multiple deep vein thrombosis. What is the appropriate reversal agent to administer to the patient at this time?
idarucizumab
Which of the following drug is approved as an adjunct during percutaneous coronary intervention (PCI) to reduce thrombotic events in select patients?
Cangrelor
Which of the following drug carries a black box warning for diminished effectiveness with concomitant use of aspirin doses above 100 mg?
Ticagrelor
Which of the following is used for the prophylaxis or treatment of venous thromboembolism in patients with heparin-induced thrombocytopenia (HIT), and it is also approved for use during percutaneous coronary intervention (PCI) in patients who have or are at risk for developing HIT?
Argatroban
Which of the following drug is a recombinant modified factor Xa protein approved by the FDA in May 2018 for the reversal of apixaban and rivaroxaban in patients with life-threatening or uncontrolled bleeding?
Andexanet alfa
Which of the following drug is a synthetically derived pentasaccharide anticoagulant that selectively inhibits factor Xa. By selectively binding to antithrombin III, fondaparinux potentiates (300- to 1000-fold) the innate neutralization of factor Xa by antithrombin III and approved for use in the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and for the prophylaxis of venous thromboembolism in the setting of orthopedic and abdominal surgery.
Fondaparinux
Which of the following drugs is an oral direct thrombin inhibitor and is used or the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation?
Dabigatran
Which is most appropriate for reversing the anticoagulant effects of heparin?
protamine sulfate
Concerning anticoagulants, all of the following are correct except
Warfarin is the preferred anticoagulant in pregnant women
Which of the following anti-platelet durg (a humanized monoclonal antibody) is glycoprotein IIb/IIIa and vitronectin receptor antagonist?
Abcimixab
Which of the P2Y12 ADP receptor antagonists reversibly binds the receptor?
Ticagrelor
Which must heparin bind to in order to exert its anticoagulant effect?
Antithrombin III
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