Hyperlipidaemia an der University Of Hertfordshire | Karteikarten & Zusammenfassungen

Lernmaterialien für Hyperlipidaemia an der University of Hertfordshire

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What drug increases simvastatin concentration?

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Grape fruit juice

Ketoconazole

Miconazole

Clarithromycin 

Erythromycin

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What is the max dose of simvastatin if the patient is also taking amiodarone or rate limiting CCB (verapamil or diltiazem)

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max dose of simvastatin is 20mg

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What drug is most effective in reducing triglycerides?

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Fibrates

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What is familial hypercholesterolemia?

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Familial hypercholesterolemia (FH) is an inherited defect in how the body recycles LDL (bad) cholesterol.

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What drugs cause hyperlipidaemia?

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  • Antipsychotics (especially first generation)
  • Immunosuppressants
  • Antiretroviral
  • Corticosteroids
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what is the indication of nicotinic acid ?

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used to lower triglycerides and LDL

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Why is thyroid function relevant in hyperlipidaemia?

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Hypothyroidism can cause abnormal lipid levels.


First check thyroid function or treat with thyroid replacement drugs before initiating statins

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What are the monitoring requirements for statins?


What is the aim of statin treatment? (what reduction value)

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Lipid profile 3 months after starting statin (total cholesterol, LDL, HDL and triglycerides)


Aim for reduction in non-HDL cholesterol of more than 40%

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Secondary causes of dyslipidaemia should be address before starting statins. List the secondary causes

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Diabetes

Hepatic disease

Excess alcohol consumption

Hypothyroidism

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What causes hyperlipidaemia?

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  • Liver or kidney disease
  • Family history for high cholesterol
  • Diabetes
  • Hypothyroidism
  • Life style factors (smoking, obesity, diet)
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TESTE DEIN WISSEN

What three statins are used in high intensity and at what strengths?

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TESTE DEIN WISSEN

Atorvastatin

20mg

40mg

80mg


Rosuvastatin

10mg

20mg

40mg


Simvastatin

80mg

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Can you use nicotinic acid, bile acids sequestrants and omega 3 fatty acids compound in primary and secondary prevention of CVD?

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not recommended

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  • 1 Lernmaterialien

Beispielhafte Karteikarten für deinen Hyperlipidaemia Kurs an der University of Hertfordshire - von Kommilitonen auf StudySmarter erstellt!

Q:

What drug increases simvastatin concentration?

A:

Grape fruit juice

Ketoconazole

Miconazole

Clarithromycin 

Erythromycin

Q:

What is the max dose of simvastatin if the patient is also taking amiodarone or rate limiting CCB (verapamil or diltiazem)

A:

max dose of simvastatin is 20mg

Q:

What drug is most effective in reducing triglycerides?

A:

Fibrates

Q:

What is familial hypercholesterolemia?

A:

Familial hypercholesterolemia (FH) is an inherited defect in how the body recycles LDL (bad) cholesterol.

Q:

What drugs cause hyperlipidaemia?

A:
  • Antipsychotics (especially first generation)
  • Immunosuppressants
  • Antiretroviral
  • Corticosteroids
Mehr Karteikarten anzeigen
Q:

what is the indication of nicotinic acid ?

A:

used to lower triglycerides and LDL

Q:

Why is thyroid function relevant in hyperlipidaemia?

A:

Hypothyroidism can cause abnormal lipid levels.


First check thyroid function or treat with thyroid replacement drugs before initiating statins

Q:

What are the monitoring requirements for statins?


What is the aim of statin treatment? (what reduction value)

A:

Lipid profile 3 months after starting statin (total cholesterol, LDL, HDL and triglycerides)


Aim for reduction in non-HDL cholesterol of more than 40%

Q:

Secondary causes of dyslipidaemia should be address before starting statins. List the secondary causes

A:

Diabetes

Hepatic disease

Excess alcohol consumption

Hypothyroidism

Q:

What causes hyperlipidaemia?

A:
  • Liver or kidney disease
  • Family history for high cholesterol
  • Diabetes
  • Hypothyroidism
  • Life style factors (smoking, obesity, diet)
Q:

What three statins are used in high intensity and at what strengths?

A:

Atorvastatin

20mg

40mg

80mg


Rosuvastatin

10mg

20mg

40mg


Simvastatin

80mg

Q:

Can you use nicotinic acid, bile acids sequestrants and omega 3 fatty acids compound in primary and secondary prevention of CVD?

A:

not recommended

Hyperlipidaemia

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