Amiodarone & Digoxin an der University Of Hertfordshire | Karteikarten & Zusammenfassungen

Lernmaterialien für Amiodarone & Digoxin an der University of Hertfordshire

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What are the monitoring requirements for amiodarone?

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  • Thyroid function test
  • Liver function test
  • Serum K+ concentration (causes hypokalaemia)
  • Chest X-ray
  • Annual eye test
  • ECG (with IV use) and blood pressure
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What patient group is more susceptible to digitalis toxicity?

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Elderly patients, therefore monitor and reduce dose where appropriate

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What is digoxin used in?

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Controlling AF

Atrial flutter

Heart failure

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How is digoxin maintenance dose determined?

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It is determined by the ventricular rate at rest, should not fall below 60bpm

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If the patient experiences nausea whilst taking digoxin, how can this be managed?

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Dose can be divided into 2 doses. 


E.g. if total daily dose is 100mcg

Patient will take 50mcg in morning and 50mcg in evening

 


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What is digoxin using the mnemonic 2KIDNEYS?

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2 - two therapeutic ranges for digoxin 1 to 2 mcg/L but toxicity can occur from 1.5mcg/L and higher so monitoring required at 1.5mcg/L

 

K - Potassium (low potassium concentration increases digoxin toxicity)

 

I - Inotrope (positive ionotropic drug)

 

D - Decreased K+ leads to increased digoxin toxicity

 

N - Nausea

 

E - Emesis (vomiting)

 

Y - Yellow vision

 

S - K+ sparing diuretic (spironolactone) (prevents potassium loss)

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What is the dose of digoxin when treating AF?

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125-250mcg once daily

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What effect does digoxin have on vision?

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Turns vision yellow

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How long does it take for digoxin to work?

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Takes several hours for effect, therefore not suitable for rapid HR control

 


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At what mcg/L should digoxin be monitored?

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TESTE DEIN WISSEN

Therapeutic range is 1 to 2 mcg/L

 

However

toxicity can occur from 1.5mcg/L onwards so monitor from 1.5.

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What are the interactions of amiodarone?

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Amiodarone is an enzyme inhibitor

 

Increases plasma concentration

Warfarin, digoxin, ciclosporins and phenytoin

 

Increased risk of arrhythmias when given with lithium

 

Increased risk myopathy when given with statins

 

QT prolongation risk when taking with

Antidepressants, antipsychotics, lithium, macrolides and quinolones

 

Amiodarone has long half life therefore interactions can occur several weeks and months after drug treatment as stopped.

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What drugs decrease potassium levels thus affecting digoxin?

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Loop diuretics

Thiazide diuretics

Theophylline

Steroids

 

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  • 1307 Karteikarten
  • 133 Studierende
  • 1 Lernmaterialien

Beispielhafte Karteikarten für deinen Amiodarone & Digoxin Kurs an der University of Hertfordshire - von Kommilitonen auf StudySmarter erstellt!

Q:

What are the monitoring requirements for amiodarone?

A:
  • Thyroid function test
  • Liver function test
  • Serum K+ concentration (causes hypokalaemia)
  • Chest X-ray
  • Annual eye test
  • ECG (with IV use) and blood pressure
Q:

What patient group is more susceptible to digitalis toxicity?

A:

Elderly patients, therefore monitor and reduce dose where appropriate

Q:

What is digoxin used in?

A:

Controlling AF

Atrial flutter

Heart failure

Q:

How is digoxin maintenance dose determined?

A:

It is determined by the ventricular rate at rest, should not fall below 60bpm

Q:

If the patient experiences nausea whilst taking digoxin, how can this be managed?

A:

Dose can be divided into 2 doses. 


E.g. if total daily dose is 100mcg

Patient will take 50mcg in morning and 50mcg in evening

 


Mehr Karteikarten anzeigen
Q:

What is digoxin using the mnemonic 2KIDNEYS?

A:

2 - two therapeutic ranges for digoxin 1 to 2 mcg/L but toxicity can occur from 1.5mcg/L and higher so monitoring required at 1.5mcg/L

 

K - Potassium (low potassium concentration increases digoxin toxicity)

 

I - Inotrope (positive ionotropic drug)

 

D - Decreased K+ leads to increased digoxin toxicity

 

N - Nausea

 

E - Emesis (vomiting)

 

Y - Yellow vision

 

S - K+ sparing diuretic (spironolactone) (prevents potassium loss)

Q:

What is the dose of digoxin when treating AF?

A:

125-250mcg once daily

Q:

What effect does digoxin have on vision?

A:

Turns vision yellow

Q:

How long does it take for digoxin to work?

A:

Takes several hours for effect, therefore not suitable for rapid HR control

 


Q:

At what mcg/L should digoxin be monitored?

A:

Therapeutic range is 1 to 2 mcg/L

 

However

toxicity can occur from 1.5mcg/L onwards so monitor from 1.5.

Q:

What are the interactions of amiodarone?

A:

Amiodarone is an enzyme inhibitor

 

Increases plasma concentration

Warfarin, digoxin, ciclosporins and phenytoin

 

Increased risk of arrhythmias when given with lithium

 

Increased risk myopathy when given with statins

 

QT prolongation risk when taking with

Antidepressants, antipsychotics, lithium, macrolides and quinolones

 

Amiodarone has long half life therefore interactions can occur several weeks and months after drug treatment as stopped.

Q:

What drugs decrease potassium levels thus affecting digoxin?

A:

Loop diuretics

Thiazide diuretics

Theophylline

Steroids

 

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