Immunology: B-cell Activation And Secondary Lymphoid Organs an der Hochschule Bonn-Rhein-Sieg | Karteikarten & Zusammenfassungen

Lernmaterialien für Immunology: B-cell Activation and Secondary Lymphoid Organs an der Hochschule Bonn-Rhein-Sieg

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Where are B-cells activated? 
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In follicles/B-cell zones
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Where are follicles/B-cell zones present? 
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In all secondary lymphoid organs 
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From where do lymph nodes filter/collect antigens? 
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From tissues throughout the body
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From where does spleen filter/collect antigens? 
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from the blood 
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From where does MALT filter/collect antigens?
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from the mucosal surface
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Which criteria have to be met by the secondary lymphoid organs to activate B-/T-cells?
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1. allow entry of antigen

2. allow entry of naive B- and T-cells through HEV

3. must have areas for interactions between B- and T-cells

4. must allow effector (mature) cells and their molecules (e.g. antibodies) to exit
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In the lymph node, the follicle can be divided into how many parts? Which ones and what do they contain? 
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1. primary follicles (contain only naive B-cells)

2. secondary follicles (contain both mature and naive B-cells)
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The secondary follicle of the lymph node is subdivided into three parts. Which ones and what do they contain? 
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1. Germinal center (contains cluster of active B-cells)

2. Corona (contains naive B-cells that migrate to germinal center once activated)

3. Paracortex (contains T-cell areas and APCs alongside the HEV)
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How is the spleen subdivided and what are the different parts responsible for? 
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1. Red pulp (responsible for filtering old blood cells)

2. White pulp (responsible for T- and B-cell activation) 
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How are naive B- and T-cells carried through the white pulp
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by blood vessels
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Where are B-cells found in the spleen? Where are T-cells found in the spleen? 
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TESTE DEIN WISSEN
B-cells: In follicles 

T-cells: in Peri-arteriolar lymphoid sheath (PALS) 
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Where are T-cells activated?
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TESTE DEIN WISSEN
in the T-cell zone
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  • 32 Lernmaterialien

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Q:
Where are B-cells activated? 
A:
In follicles/B-cell zones
Q:
Where are follicles/B-cell zones present? 
A:
In all secondary lymphoid organs 
Q:
From where do lymph nodes filter/collect antigens? 
A:
From tissues throughout the body
Q:
From where does spleen filter/collect antigens? 
A:
from the blood 
Q:
From where does MALT filter/collect antigens?
A:
from the mucosal surface
Mehr Karteikarten anzeigen
Q:
Which criteria have to be met by the secondary lymphoid organs to activate B-/T-cells?
A:
1. allow entry of antigen

2. allow entry of naive B- and T-cells through HEV

3. must have areas for interactions between B- and T-cells

4. must allow effector (mature) cells and their molecules (e.g. antibodies) to exit
Q:
In the lymph node, the follicle can be divided into how many parts? Which ones and what do they contain? 
A:
1. primary follicles (contain only naive B-cells)

2. secondary follicles (contain both mature and naive B-cells)
Q:
The secondary follicle of the lymph node is subdivided into three parts. Which ones and what do they contain? 
A:
1. Germinal center (contains cluster of active B-cells)

2. Corona (contains naive B-cells that migrate to germinal center once activated)

3. Paracortex (contains T-cell areas and APCs alongside the HEV)
Q:
How is the spleen subdivided and what are the different parts responsible for? 
A:
1. Red pulp (responsible for filtering old blood cells)

2. White pulp (responsible for T- and B-cell activation) 
Q:
How are naive B- and T-cells carried through the white pulp
A:
by blood vessels
Q:
Where are B-cells found in the spleen? Where are T-cells found in the spleen? 
A:
B-cells: In follicles 

T-cells: in Peri-arteriolar lymphoid sheath (PALS) 
Q:
Where are T-cells activated?
A:
in the T-cell zone
Immunology: B-cell Activation and Secondary Lymphoid Organs

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