1. Semester6 ECTS
Advanced Biochemistry and Molecular Medicine
Lecture series organized in 6 blocks covering structure & proteomics, extracellular matrix & transport, metabolism & hereditary disease, mitochondria & death/immunity/cancer, regulation & proteostasis, and engineering & tools. Research-oriented interactive lectures introducing advanced concepts and technologies in biochemistry and molecular medicine.
1. Semester12 ECTS
Medical Biochemistry
Subject module covering protein purification, enzyme kinetics, protein-interaction analysis, biogenesis of cofactors and coenzymes, nucleotide and amino acid metabolism, and inborn errors in metabolism. Includes lectures, hands-on laboratory work, and seminar.
1. Semester12 ECTS
Molecular Concepts of Human Diseases
Subject module focusing on molecular mechanisms of diseases related to mutated proteins in organelles, immune system, mitochondria, and extracellular matrix. Covers experimental techniques including flow cytometry, surface plasmon resonance, gene expression analysis, and mitochondrial dysfunction analysis.
1. Semester12 ECTS
Epigenetics
Subject module providing broad insight into epigenetics mechanisms, regulation, and misregulation in human diseases. Covers technologies like sequencing, FISH, and chromatin analysis; includes laboratory work with epigenetic projects and bioinformatics skills for high-throughput data analysis.
1. Semester12 ECTS
Metabolic Reprogramming in Health and Diseases
Subject module on fundamental principles of metabolic concepts in health and disease states. Introduces state-of-the-art methodologies in cell biology, biochemistry, and molecular biology for studying metabolic processes.
1. Semester12 ECTS
Genetic Tools for Investigating Biochemical Interactions
Subject module covering genetic approaches and tools for studying biochemical interactions in living systems. Includes molecular genetic techniques for investigating protein-protein and protein-nucleic acid interactions.
2. Semester6 ECTS
Hot Topics in Biochemistry and Molecular Medicine
Seminar and exercise module covering publication search, statistical tools, disease mechanisms, novel discoveries, and therapies in biochemistry and molecular medicine. Students determine contents to a large extent and present hot topics with peer review and audience interaction.
2. Semester12 ECTS
Molecular Pathology
Subject module covering molecular mechanisms of disease pathology. Focuses on understanding disease processes at the molecular level using various analytical techniques.
2. Semester12 ECTS
3D Cryo Electron Microscopy
Subject module on three-dimensional cryo-electron microscopy techniques for structural determination of proteins and complexes at high resolution.
2. Semester12 ECTS
Neurobiochemistry
Subject module focusing on biochemical processes in the nervous system. Covers neuronal metabolism, neurotransmitter systems, and molecular mechanisms relevant to neurobiology.
2. Semester6 ECTS
Scientific Writing
Workshop module developing strategic writing approaches for scientific communication. Covers scientific publication standards, text organization, data visualization, and use of software tools for scientific writing.
2. Semester18 ECTS
Laboratory Project Module 1
Research project of 12 weeks duration where students work independently in a research group on a scientific question to develop deeper understanding of experimental methods and techniques.
3. Semester12 ECTS
Advanced Structural Biology: Crystallography, BioNMR, and Predictive Modeling
Subject module on advanced structural biology techniques including crystallography, nuclear magnetic resonance spectroscopy, and computational modeling approaches for analyzing biomolecular structures.
3. Semester12 ECTS
Redox Metabolism
Subject module on redox-active metabolic pathways and processes. Focuses on cellular redox balance, electron transfer, and redox-sensitive signaling mechanisms in biochemistry.
3. Semester12 ECTS
Proteostasis in Health and Disease
Subject module on protein homeostasis mechanisms, including synthesis, folding, quality control, and degradation. Covers pathological consequences of proteostasis imbalance in disease.
3. Semester18 ECTS
Laboratory Project Module 2
Second research project of 12 weeks duration conducted in a different research group than the first project, ensuring broad practical training and exposure to diverse research methodologies.
3. Semester6 ECTS
Project Proposal
Module where students write an application for research funding related to their future master thesis topic. Includes state-of-the-art review, relevant figures or graphical abstract, and work program formatted according to DFG standards.
4. Semester36 ECTS
Master's Thesis and Defense
Six-month research project resulting in a master's thesis and colloquium presentation. Represents the integrative final component of the program.
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