Endocrine Disorders at Waterford Institute Of Technology | Flashcards & Summaries

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Lernmaterialien für endocrine disorders an der Waterford Institute Of Technology

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TESTE DEIN WISSEN
Treatment of hyperthyroidism 
Lösung anzeigen
TESTE DEIN WISSEN
Surgical removal of thyroid gland
Proplythiouracil administer weeks before surgery so basal metabolic rate has returned to norms 
Admin of high conc of iodides for 2 wks prior to operation causes gland to decrease 
Hyperplastic gland = radioactive therapy 
Long term meds 
Lösung ausblenden
TESTE DEIN WISSEN
Causes and Pathophysiology of hyperthyroidism 
Lösung anzeigen
TESTE DEIN WISSEN
Toxic goiter, Graves’ disease, thyrotoxicosis 
Thyroid gland increased with hyperplasia which is an increase in cells number- increases rate of secretion 
Similar changes caused by excessive TSH but TSH conc found to be less than normal rather than enhanced 
Thyroid stimulating antibodies have stimulating effect on thyroid this supresses pituitary formation of TSH 
Lösung ausblenden
TESTE DEIN WISSEN
Hypopituitarism in the adult
Lösung anzeigen
TESTE DEIN WISSEN
Decreased secretion of all anterior pituitary hormones 

Caused by - tumorous condition that compress pituitary gland until function destroyed 

Thrombosis of the pituitary blood vessels shock after baby 

Effects - hypothyroidism, decrease in glucocorticoids and gonadotropic hormones 
Lösung ausblenden
TESTE DEIN WISSEN
Cretinism
Lösung anzeigen
TESTE DEIN WISSEN
Caused by extreme hypothyroidism during feral life , infancy and childhood 
Failure of growth and cognitive deficits 

Results from congenital lack of thyroid gland 
Failure of thyroid gland to produce thyroid hormone from genetic defect 
Iodine lack in diet 

Treatment - return of growth needs to be treated within a few weeks of birth 
Lack of growth in the CNS 
Lösung ausblenden
TESTE DEIN WISSEN
Adrenal disorders - the adrenal glands 
Lösung anzeigen
TESTE DEIN WISSEN
Paired glands on top of kidneys 
  • 2 regions
  • Adrenal cortex secretes steroid hormones
  • Adrenal medulla secretes catecholamine hormones 
Adrenal cortex hormones 
  • Minerslcorticoids: aldosterone 
  • Glucocorticoids: cortisol 
  • Androgens 
Lösung ausblenden
TESTE DEIN WISSEN
Hypoadrenalism- Addison’s disease 
Lösung anzeigen
TESTE DEIN WISSEN
Failure of adrenal cortex to produce adrenocortical hormones 
Caused by Autoimmunity against cortices, and by infection of adrenal gland or invasion of adrenal cortices by cancer 
Lösung ausblenden
TESTE DEIN WISSEN
Addison’s disease S+S 
Lösung anzeigen
TESTE DEIN WISSEN
1. Mineralocorticoid deficiency 
  • Lack of aldosterone secretion , sodium, chloride and water lost in urine
2. Glucocorticoids deficiency 
  • Decreased blood glucose levels , fatigue, effects of stress susceptible. 
3. Melanin pigmentation - 
  • Skin 
Lösung ausblenden
TESTE DEIN WISSEN
Addisons treatment 
Lösung anzeigen
TESTE DEIN WISSEN
No treatment with total adrenal destruction person dies weeks from weakness and circulatory shock 

Small quantities of minerlocortoids and glucocorticoids administration daily 

Addison’s crisis- extra glucocorticoids and severe stress 
Lösung ausblenden
TESTE DEIN WISSEN
Hyperadrenalism- Cushing’s syndrome 
Lösung anzeigen
TESTE DEIN WISSEN
Hypersecretion of cortisol by the adrenal cortex causes Cushing’s disease
Abnormal amounts of cortisol, and secretion of androgens 

Substance abuse 
Lösung ausblenden
TESTE DEIN WISSEN
Acromegaly
Lösung anzeigen
TESTE DEIN WISSEN
If a tumour develops after adolescence the person cannot grow taller but the softer shoes can continue to grow and the bones can grow in thickness enlargement is especially marked in the bones of the hands and feet news in vertebrae jaw protrudes forward forehead slants forward fingers Thicken and hunchback many soft tissues such as tongue liver kidneys become greatly enlarged 
Lösung ausblenden
TESTE DEIN WISSEN
S+s of hyperthyroidism 
Lösung anzeigen
TESTE DEIN WISSEN
Intolerant to heat
Sweating 
Weight loss 
Diarrhoea
Muscle weakness 
Nervous
Fatigue 
Tremor
Big eyeballs 
Lösung ausblenden
TESTE DEIN WISSEN
Hypothyroidism S+S
Lösung anzeigen
TESTE DEIN WISSEN
Fatigue 
Sleepiness 
Sluggish muscles slow heart rate 
Constipation 
Mental slowness 
Low temp 
Lösung ausblenden
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Q:
Treatment of hyperthyroidism 
A:
Surgical removal of thyroid gland
Proplythiouracil administer weeks before surgery so basal metabolic rate has returned to norms 
Admin of high conc of iodides for 2 wks prior to operation causes gland to decrease 
Hyperplastic gland = radioactive therapy 
Long term meds 
Q:
Causes and Pathophysiology of hyperthyroidism 
A:
Toxic goiter, Graves’ disease, thyrotoxicosis 
Thyroid gland increased with hyperplasia which is an increase in cells number- increases rate of secretion 
Similar changes caused by excessive TSH but TSH conc found to be less than normal rather than enhanced 
Thyroid stimulating antibodies have stimulating effect on thyroid this supresses pituitary formation of TSH 
Q:
Hypopituitarism in the adult
A:
Decreased secretion of all anterior pituitary hormones 

Caused by - tumorous condition that compress pituitary gland until function destroyed 

Thrombosis of the pituitary blood vessels shock after baby 

Effects - hypothyroidism, decrease in glucocorticoids and gonadotropic hormones 
Q:
Cretinism
A:
Caused by extreme hypothyroidism during feral life , infancy and childhood 
Failure of growth and cognitive deficits 

Results from congenital lack of thyroid gland 
Failure of thyroid gland to produce thyroid hormone from genetic defect 
Iodine lack in diet 

Treatment - return of growth needs to be treated within a few weeks of birth 
Lack of growth in the CNS 
Q:
Adrenal disorders - the adrenal glands 
A:
Paired glands on top of kidneys 
  • 2 regions
  • Adrenal cortex secretes steroid hormones
  • Adrenal medulla secretes catecholamine hormones 
Adrenal cortex hormones 
  • Minerslcorticoids: aldosterone 
  • Glucocorticoids: cortisol 
  • Androgens 
Mehr Karteikarten anzeigen
Q:
Hypoadrenalism- Addison’s disease 
A:
Failure of adrenal cortex to produce adrenocortical hormones 
Caused by Autoimmunity against cortices, and by infection of adrenal gland or invasion of adrenal cortices by cancer 
Q:
Addison’s disease S+S 
A:
1. Mineralocorticoid deficiency 
  • Lack of aldosterone secretion , sodium, chloride and water lost in urine
2. Glucocorticoids deficiency 
  • Decreased blood glucose levels , fatigue, effects of stress susceptible. 
3. Melanin pigmentation - 
  • Skin 
Q:
Addisons treatment 
A:
No treatment with total adrenal destruction person dies weeks from weakness and circulatory shock 

Small quantities of minerlocortoids and glucocorticoids administration daily 

Addison’s crisis- extra glucocorticoids and severe stress 
Q:
Hyperadrenalism- Cushing’s syndrome 
A:
Hypersecretion of cortisol by the adrenal cortex causes Cushing’s disease
Abnormal amounts of cortisol, and secretion of androgens 

Substance abuse 
Q:
Acromegaly
A:
If a tumour develops after adolescence the person cannot grow taller but the softer shoes can continue to grow and the bones can grow in thickness enlargement is especially marked in the bones of the hands and feet news in vertebrae jaw protrudes forward forehead slants forward fingers Thicken and hunchback many soft tissues such as tongue liver kidneys become greatly enlarged 
Q:
S+s of hyperthyroidism 
A:
Intolerant to heat
Sweating 
Weight loss 
Diarrhoea
Muscle weakness 
Nervous
Fatigue 
Tremor
Big eyeballs 
Q:
Hypothyroidism S+S
A:
Fatigue 
Sleepiness 
Sluggish muscles slow heart rate 
Constipation 
Mental slowness 
Low temp 
endocrine disorders

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