Pancreatitis at University Of Witwatersrand | Flashcards & Summaries

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Lernmaterialien für pancreatitis an der University of Witwatersrand

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What is chronic pancreatitis
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Persistent inflammation of the pancreas related to outbursts of acute pancreatitis
Is irreversible
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TESTE DEIN WISSEN
Tx of chronic pancreatitis
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TESTE DEIN WISSEN
Control pain 
Control risk factors: reduce ETOH, meat and obesity
Enzymes
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TESTE DEIN WISSEN

Digestive enzymes secreted by pancrease

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-lipase (increase in blood and result in fatty necrosis of the pancreas)
-amylase (will increase in the blood and helps diagnose pancreatitis 
-protease ( damage cells and vasculature when released)
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Investigations
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- serum amylase and lipase
Ultrasound
ABG
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Treatment of acute pancreatitis
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Nil Po 
Maxalon, 10 mg p.o daily
Panadol, 1g, p.o, prn
IV
Catheter
Lösung ausblenden
TESTE DEIN WISSEN

Complication of acute pancreatitis

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-chronic pancreatitis
Pancreatic ascites 
Acute lung injury 
Pancreatic effusion
Infected pancreatic necrosis
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Causs of pancreatitis
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Gallstones
ETOH
Toxins / trauma
Scorpion poison
Mumps
Autoimmune condition
Steroids
Hyperlipidemia
ERCP
Drugs
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TESTE DEIN WISSEN
Complication of chronic pancreatitis
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TESTE DEIN WISSEN
DM due to inability to create insulin
Psuedocysts 
Pancreatic ca
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Pathophysiology of chronic pancreatitis

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Repeated bouts of acute pancreatitis leads to ductal dilatation and damage to pancreatic tissue. This activates stellate cells in the pancreas  to make fibrotic tissue tht narrows and stenosis of the duct and acinar cells atrophy which leads to healthy cells being replaced by mishaped ducts, calcium deposits and fibrosis
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Exocrine vs endocrine actions of the pancreas
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TESTE DEIN WISSEN
Exocrine- secretes digestive enzymes to the duodenum 
Endocrine - secretes hormones to the blood, i.e: insulin and glucagon
Lösung ausblenden
TESTE DEIN WISSEN
What is acute pancreatitis
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TESTE DEIN WISSEN
Inflammation of the pancreas by enzyme mediated auto digestion 
Sudden onset and resolved in days 
Caused by gallstones and alcohol
Inflammation ranges from mild oedema to Peri pancreatic necrosis
Lösung ausblenden
TESTE DEIN WISSEN
Pathophysiology of acute pancreatitis
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TESTE DEIN WISSEN
Inflammation of part of the pancreas e which leads to the inflammation and damage of the acinar cells which leads to them releasing unintentionally the digestive enzymes which further damages surrounding structures
Lösung ausblenden
  • 40115 Karteikarten
  • 3451 Studierende
  • 33 Lernmaterialien

Beispielhafte Karteikarten für deinen pancreatitis Kurs an der University of Witwatersrand - von Kommilitonen auf StudySmarter erstellt!

Q:
What is chronic pancreatitis
A:
Persistent inflammation of the pancreas related to outbursts of acute pancreatitis
Is irreversible
Q:
Tx of chronic pancreatitis
A:
Control pain 
Control risk factors: reduce ETOH, meat and obesity
Enzymes
Q:

Digestive enzymes secreted by pancrease

A:
-lipase (increase in blood and result in fatty necrosis of the pancreas)
-amylase (will increase in the blood and helps diagnose pancreatitis 
-protease ( damage cells and vasculature when released)
Q:
Investigations
A:
- serum amylase and lipase
Ultrasound
ABG
Q:
Treatment of acute pancreatitis
A:
Nil Po 
Maxalon, 10 mg p.o daily
Panadol, 1g, p.o, prn
IV
Catheter
Mehr Karteikarten anzeigen
Q:

Complication of acute pancreatitis

A:
-chronic pancreatitis
Pancreatic ascites 
Acute lung injury 
Pancreatic effusion
Infected pancreatic necrosis
Q:
Causs of pancreatitis
A:
Gallstones
ETOH
Toxins / trauma
Scorpion poison
Mumps
Autoimmune condition
Steroids
Hyperlipidemia
ERCP
Drugs
Q:
Complication of chronic pancreatitis
A:
DM due to inability to create insulin
Psuedocysts 
Pancreatic ca
Q:

Pathophysiology of chronic pancreatitis

A:
Repeated bouts of acute pancreatitis leads to ductal dilatation and damage to pancreatic tissue. This activates stellate cells in the pancreas  to make fibrotic tissue tht narrows and stenosis of the duct and acinar cells atrophy which leads to healthy cells being replaced by mishaped ducts, calcium deposits and fibrosis
Q:
Exocrine vs endocrine actions of the pancreas
A:
Exocrine- secretes digestive enzymes to the duodenum 
Endocrine - secretes hormones to the blood, i.e: insulin and glucagon
Q:
What is acute pancreatitis
A:
Inflammation of the pancreas by enzyme mediated auto digestion 
Sudden onset and resolved in days 
Caused by gallstones and alcohol
Inflammation ranges from mild oedema to Peri pancreatic necrosis
Q:
Pathophysiology of acute pancreatitis
A:
Inflammation of part of the pancreas e which leads to the inflammation and damage of the acinar cells which leads to them releasing unintentionally the digestive enzymes which further damages surrounding structures
pancreatitis

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