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Hemorrhage of blood into small areas of skin, mucous membranes, and other tissues
Purpura
Triad of:
1. Thrombocytopenia
2. Recurrent infections
3. Eczema
Wiskott-Aldrich Syndrome
Purplish red pinpoint hemorrhagic spots in the skin caused by loss of capillary ability to withstand normal blood pressure and trauma
Petechiae
Which of the following is not true on thrombocytosis?
Primary Origin - Myeloproliferative disorder associated with thrombocytosis
Deficiency in GP Ib/IX/V complex; Lack of adhesion to VWF and abnormal response to thrombin; Characterized by giant platelets, thrombocytopenia, and reduced survival
Bernard Soulier Syndrome
Deficiency of von Willebrand Factor;
Von Willebrand Disease
Triad of:
1. Tyrosinase-positive albinism
2. Accumulation of ceroid like
pigment in macrophage
3. Bleeding tendencies
Hermansky-Pudlak Syndrome
Swelling or tumor in the tissues or a body cavity that contains clotted blood
Hematoma
Resemble thrombocytopenia except that there is a normal platelet count; either inherited or acquired
THROMBOCYTOPATHY
Triad of:
1. Albinism
2. Recurrent
infections
3. Giant lysosomes in all granule containing cells
Chediak-Higashi syndrome
Form of purpura in which blood escapes into large areas of skin and mucous membranes, but not into deep tissues
Ecchymosis
The patient becomes thrombocytopenic only when production capacity is no longer compensated
True
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