Pathology at University Of KwaZulu-Natal | Flashcards & Summaries

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Lernmaterialien für Pathology an der University of KwaZulu-Natal

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Where are the plasma derived mediators produced?


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liver 

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which cells  are mostly found in a purulent exudate

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neutrophils and debris of dead cells  

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give the critical function of inflammation 

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it is to deliver leukocytes to the site of injury and activate them to perform their normal functions in host defense 

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Function of NSAIDs


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inhibits prostaglandins synthesis 

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give the 4 mediators of inflammation( VLCC)

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vasoactive amines 

lipid products(prostaglandins & leukotrienes)

cytokines and chemokines 

complement activation 

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give the 5 signs of inflammation

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pain 

swelling

Redness 

heat

loss of function 


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which cells are present in chronic inflammation

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lymphocytes 

microphages 

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6 causes of inflammation 

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trauma (burns )

physical or chemical injury 

foreign bodies

infections 

immune rxn

inappropriate rxn against environmental substances

tissue necrosis

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give the mediators of defence 

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phagocytic leukocytes

antibodies 

complement proteins 

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give the two events that take place in acute inflammation

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vascular changes 

cellular events 

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when does the acute inflammation progress to chronic inflammation 

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When the defense cells fail to eliminate the stimulus 

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give the sequence of inflammation 

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1. The offending agent, which is located in __extravascualr tissue, is recognized by host cells
and molecules.
2. Leukocytes and plasma proteins are recruited from the circulation to the site where the
offending agent is located.
3. The leukocytes and proteins are activated and work together to destroy and eliminate the
offending substance.
4. The reaction is controlled and terminated.
5. The damaged tissue is repaired

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Q:

Where are the plasma derived mediators produced?


A:

liver 

Q:

which cells  are mostly found in a purulent exudate

A:

neutrophils and debris of dead cells  

Q:

give the critical function of inflammation 

A:

it is to deliver leukocytes to the site of injury and activate them to perform their normal functions in host defense 

Q:

Function of NSAIDs


A:

inhibits prostaglandins synthesis 

Q:

give the 4 mediators of inflammation( VLCC)

A:

vasoactive amines 

lipid products(prostaglandins & leukotrienes)

cytokines and chemokines 

complement activation 

Mehr Karteikarten anzeigen
Q:

give the 5 signs of inflammation

A:

pain 

swelling

Redness 

heat

loss of function 


Q:

which cells are present in chronic inflammation

A:

lymphocytes 

microphages 

Q:

6 causes of inflammation 

A:

trauma (burns )

physical or chemical injury 

foreign bodies

infections 

immune rxn

inappropriate rxn against environmental substances

tissue necrosis

Q:

give the mediators of defence 

A:

phagocytic leukocytes

antibodies 

complement proteins 

Q:

give the two events that take place in acute inflammation

A:

vascular changes 

cellular events 

Q:

when does the acute inflammation progress to chronic inflammation 

A:

When the defense cells fail to eliminate the stimulus 

Q:

give the sequence of inflammation 

A:

1. The offending agent, which is located in __extravascualr tissue, is recognized by host cells
and molecules.
2. Leukocytes and plasma proteins are recruited from the circulation to the site where the
offending agent is located.
3. The leukocytes and proteins are activated and work together to destroy and eliminate the
offending substance.
4. The reaction is controlled and terminated.
5. The damaged tissue is repaired

Pathology

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