ENDOCRINE SYSTEM at Universiti Sultan Zainal Abidin | Flashcards & Summaries

Select your language

Suggested languages for you:
Log In Start studying!

Lernmaterialien für ENDOCRINE SYSTEM an der Universiti Sultan Zainal Abidin

Greife auf kostenlose Karteikarten, Zusammenfassungen, Übungsaufgaben und Altklausuren für deinen ENDOCRINE SYSTEM Kurs an der Universiti Sultan Zainal Abidin zu.

TESTE DEIN WISSEN

Based on mechanism of action, the hormones may
be classified into two which are?

Lösung anzeigen
TESTE DEIN WISSEN


Group I. Hormones with cell surface receptors
Group II. Hormones with intracellular receptors.

Lösung ausblenden
TESTE DEIN WISSEN

Stimuli for inhibiting the secretion hypothalamic TRH

Lösung anzeigen
TESTE DEIN WISSEN

high T3 & T4

Lösung ausblenden
TESTE DEIN WISSEN

Colloid 

Lösung anzeigen
TESTE DEIN WISSEN
  • Produced by follicular cells
  • inside the follicles
  • serve as reservoir of materials for thyroid hormone (thyroxine and triiodothyronine) production
  • act as reservoir for the hormones themselves
  • rich in a protein called thyroglobulin
Lösung ausblenden
TESTE DEIN WISSEN

Membrane receptors:

Lösung anzeigen
TESTE DEIN WISSEN
  • Embedded in target cell membrane;
    integral proteins /glycoproteins;
  • penetrate through membrane
  • Bind protein & charged hormones (peptides or neurotransmitters)
Lösung ausblenden
TESTE DEIN WISSEN

Intracellular receptors ( Cytosolic/Nuclear)

Lösung anzeigen
TESTE DEIN WISSEN
  • Nuclear proteins that usually act in pairs & bind to specific Hormone Recognition Elements (HREs) = sequences on the DNA in the promoter regions of target genes
  • Bind small, hydrophobic molecules (steroids, thyroid hormones)
Lösung ausblenden
TESTE DEIN WISSEN

Pituitary gland is removed and transplanted to other part of the body?

Lösung anzeigen
TESTE DEIN WISSEN

Rate of secretion is very low

❖Hormones are synthesised in the cell body at the
hypothalamus
❖Transported in combination with “carrier” proteins called neurophysins down to the nerve ending in the posterior pituitary gland
❖Require several day to reach the gland

Lösung ausblenden
TESTE DEIN WISSEN

A child shows the following symptoms: deficient growth; failure to show sexual development; decreased ability to respond to stress.
What is the most likely cause of all these symptoms?

Lösung anzeigen
TESTE DEIN WISSEN

Destruction of the anterior pituitary or hypothalamus. These symptoms reflect  the absence of, in order, growth hormone, the gonadotropins, and ACTH (the  symptom is due to the resulting decrease in cortisol secretion). The problem is  either primary hyposecretion of anterior pituitary hormones or secondary  hyposecretion because the hypothalamus is not secreting hypophysiotropic  hormones normally.

Lösung ausblenden
TESTE DEIN WISSEN

Pituitary stalk is cut above the pituitary gland but the entire hypothalamus is left intact?

Lösung anzeigen
TESTE DEIN WISSEN

Transient decrease for a few days. Posterior pituitary hormones continue to be secrete normally by the cut end of the fibers within the hypothalamus

❖Hormones are synthesised in the cell body at the
hypothalamus
❖Transported in combination with “carrier” proteins called
neurophysins down to the nerve ending in the posterior
pituitary gland
❖Require several day to reach the gland

Lösung ausblenden
TESTE DEIN WISSEN


A person is receiving very large doses of a cortisol like drug to treat her arthritis.
What happens to her secretion of cortisol?

Lösung anzeigen
TESTE DEIN WISSEN

The high dose of the cortisol-like substance inhibits the secretion of ACTH  by feedback inhibition of (1) hypothalamic corticotropin releasing hormone  and (2) the response of the anterior pituitary to this hypophysiotropic  hormone. The lack of ACTH causes the adrenal to atrophy and decrease its  secretion of cortisol.

Lösung ausblenden
TESTE DEIN WISSEN

A person with symptoms of hypothyroidism (for example, sluggishness and intolerance to cold) is found to have abnormally low plasma concentrations
of T4, T3, and TSH. After an injection of TRH, the plasma concentrations of all three hormones increase. Where is the site of the defect leading to the
hypothyroidism?

Lösung anzeigen
TESTE DEIN WISSEN

The hypothalamus. The low basal TSH indicates either that the pituitary is  defective or that it is receiving inadequate stimulation (TRH) from the  hypothalamus. If the thyroid itself were defective, basal TSH would be  elevated because of less negative-feedback inhibition by TH. The TSH  increase in response to TRH shows that the pituitary is capable of  responding to a stimulus and so is unlikely to be defective. Therefore, the  problem is that the hypothalamus is secreting too little TRH.

Lösung ausblenden
TESTE DEIN WISSEN

Histology of thyroid gland

Lösung anzeigen
TESTE DEIN WISSEN
  1. Extremely vascularized organ
  2. Extensively blood and lymphatic capillary network surrounding the follicles
  3. Endothelial cells of capillaries is fenestrated, facilitates the passage of hormone into the blood capillaries
  4. The adrenergic fiber terminating near the basal ganglia can be visualize using radioautographic study
Lösung ausblenden
TESTE DEIN WISSEN

Explain the pyramidal lobe of thyroid gland

Lösung anzeigen
TESTE DEIN WISSEN
  • Project upwards from the isthmus
  • Usually from the left side
Lösung ausblenden
  • 2194 Karteikarten
  • 151 Studierende
  • 1 Lernmaterialien

Beispielhafte Karteikarten für deinen ENDOCRINE SYSTEM Kurs an der Universiti Sultan Zainal Abidin - von Kommilitonen auf StudySmarter erstellt!

Q:

Based on mechanism of action, the hormones may
be classified into two which are?

A:


Group I. Hormones with cell surface receptors
Group II. Hormones with intracellular receptors.

Q:

Stimuli for inhibiting the secretion hypothalamic TRH

A:

high T3 & T4

Q:

Colloid 

A:
  • Produced by follicular cells
  • inside the follicles
  • serve as reservoir of materials for thyroid hormone (thyroxine and triiodothyronine) production
  • act as reservoir for the hormones themselves
  • rich in a protein called thyroglobulin
Q:

Membrane receptors:

A:
  • Embedded in target cell membrane;
    integral proteins /glycoproteins;
  • penetrate through membrane
  • Bind protein & charged hormones (peptides or neurotransmitters)
Q:

Intracellular receptors ( Cytosolic/Nuclear)

A:
  • Nuclear proteins that usually act in pairs & bind to specific Hormone Recognition Elements (HREs) = sequences on the DNA in the promoter regions of target genes
  • Bind small, hydrophobic molecules (steroids, thyroid hormones)
Mehr Karteikarten anzeigen
Q:

Pituitary gland is removed and transplanted to other part of the body?

A:

Rate of secretion is very low

❖Hormones are synthesised in the cell body at the
hypothalamus
❖Transported in combination with “carrier” proteins called neurophysins down to the nerve ending in the posterior pituitary gland
❖Require several day to reach the gland

Q:

A child shows the following symptoms: deficient growth; failure to show sexual development; decreased ability to respond to stress.
What is the most likely cause of all these symptoms?

A:

Destruction of the anterior pituitary or hypothalamus. These symptoms reflect  the absence of, in order, growth hormone, the gonadotropins, and ACTH (the  symptom is due to the resulting decrease in cortisol secretion). The problem is  either primary hyposecretion of anterior pituitary hormones or secondary  hyposecretion because the hypothalamus is not secreting hypophysiotropic  hormones normally.

Q:

Pituitary stalk is cut above the pituitary gland but the entire hypothalamus is left intact?

A:

Transient decrease for a few days. Posterior pituitary hormones continue to be secrete normally by the cut end of the fibers within the hypothalamus

❖Hormones are synthesised in the cell body at the
hypothalamus
❖Transported in combination with “carrier” proteins called
neurophysins down to the nerve ending in the posterior
pituitary gland
❖Require several day to reach the gland

Q:


A person is receiving very large doses of a cortisol like drug to treat her arthritis.
What happens to her secretion of cortisol?

A:

The high dose of the cortisol-like substance inhibits the secretion of ACTH  by feedback inhibition of (1) hypothalamic corticotropin releasing hormone  and (2) the response of the anterior pituitary to this hypophysiotropic  hormone. The lack of ACTH causes the adrenal to atrophy and decrease its  secretion of cortisol.

Q:

A person with symptoms of hypothyroidism (for example, sluggishness and intolerance to cold) is found to have abnormally low plasma concentrations
of T4, T3, and TSH. After an injection of TRH, the plasma concentrations of all three hormones increase. Where is the site of the defect leading to the
hypothyroidism?

A:

The hypothalamus. The low basal TSH indicates either that the pituitary is  defective or that it is receiving inadequate stimulation (TRH) from the  hypothalamus. If the thyroid itself were defective, basal TSH would be  elevated because of less negative-feedback inhibition by TH. The TSH  increase in response to TRH shows that the pituitary is capable of  responding to a stimulus and so is unlikely to be defective. Therefore, the  problem is that the hypothalamus is secreting too little TRH.

Q:

Histology of thyroid gland

A:
  1. Extremely vascularized organ
  2. Extensively blood and lymphatic capillary network surrounding the follicles
  3. Endothelial cells of capillaries is fenestrated, facilitates the passage of hormone into the blood capillaries
  4. The adrenergic fiber terminating near the basal ganglia can be visualize using radioautographic study
Q:

Explain the pyramidal lobe of thyroid gland

A:
  • Project upwards from the isthmus
  • Usually from the left side
ENDOCRINE SYSTEM

Erstelle und finde Lernmaterialien auf StudySmarter.

Greife kostenlos auf tausende geteilte Karteikarten, Zusammenfassungen, Altklausuren und mehr zu.

Jetzt loslegen

Das sind die beliebtesten ENDOCRINE SYSTEM Kurse im gesamten StudySmarter Universum

Endocrine System

Our Lady of Fatima University

Zum Kurs
Endocrine System

University of the East, Ramon Magsaysay Memorial Medical Center

Zum Kurs
Endocrine system

University of Wolverhampton

Zum Kurs
Endocrine System

Fachhochschulstudiengänge Krems IMC

Zum Kurs
Endocrine system

Loughborough University

Zum Kurs

Die all-in-one Lernapp für Studierende

Greife auf Millionen geteilter Lernmaterialien der StudySmarter Community zu
Kostenlos anmelden ENDOCRINE SYSTEM
Erstelle Karteikarten und Zusammenfassungen mit den StudySmarter Tools
Kostenlos loslegen ENDOCRINE SYSTEM