Genetik für Fortgeschrittene at Universität zu Köln

CityCITY: Köln

CountryCOUNTRY: Germany

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Exemplary flashcards for Genetik für Fortgeschrittene at the Universität zu Köln on StudySmarter:

Humeral Gen

Exemplary flashcards for Genetik für Fortgeschrittene at the Universität zu Köln on StudySmarter:

Was sind homeotische Gene?

Exemplary flashcards for Genetik für Fortgeschrittene at the Universität zu Köln on StudySmarter:

Ultrabithorax Gen

Exemplary flashcards for Genetik für Fortgeschrittene at the Universität zu Köln on StudySmarter:

UAS-ey

Exemplary flashcards for Genetik für Fortgeschrittene at the Universität zu Köln on StudySmarter:

Balancer

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Sd-Gal4

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Third Multiple 3

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Curly of Oster Balancer

Exemplary flashcards for Genetik für Fortgeschrittene at the Universität zu Köln on StudySmarter:

shibire Gen

Exemplary flashcards for Genetik für Fortgeschrittene at the Universität zu Köln on StudySmarter:

decapentaplegic Gen

Exemplary flashcards for Genetik für Fortgeschrittene at the Universität zu Köln on StudySmarter:

scalloped Gen

Exemplary flashcards for Genetik für Fortgeschrittene at the Universität zu Köln on StudySmarter:

Welche Balancer gibt es und wo liegen sie?

Exemplary flashcards for Genetik für Fortgeschrittene at the Universität zu Köln on StudySmarter:

Genetik für Fortgeschrittene

Humeral Gen

Hu, dominant

zusätzliche Borsten an Schulter (Humerus)

Chromosom 3

Genetik für Fortgeschrittene

Was sind homeotische Gene?

-sind kolinear (Reihenfolge der Gene = Reihenfolge der Lokalisation)
-es gibt 2 Cluster: Antennapedia Komplex (ANT-C) mit 6 Genen & Ultrabithorax Komplex (BX-C) mit 3 Genen
-alle sind auf Chromosom 3 –> einfache Manipulation

Genetik für Fortgeschrittene

Ultrabithorax Gen

1) Ubx^130, dominant, vergrößerte Halteren, Chromosom 3

2) bx^34e, rezessiv, Halter-zu-Flügel-Transformation, Chromosom 3

Genetik für Fortgeschrittene

UAS-ey

exprimiert ey unter UAS-Promotor

in Anwesenheit von Gal4 wird ey expimiert

–> Zielort abhängig von Lokalisation von Gal4

Genetik für Fortgeschrittene

Balancer

– haben multiple Inversionen, die durch y-Strahlung verursacht wurden

– tragen dominante Mutation (erleichtert Identifizierung)

– tragen mind. 1 rezessive Lethalmutation (=homozygot lethal)

– verhindern cross-over Rekombination

Genetik für Fortgeschrittene

Sd-Gal4

exprimiert Gal4 unter sd-Promotor

sd: Flügel- & Halterenimaginalscheiben

Genetik für Fortgeschrittene

Third Multiple 3

Chromosom 3

Abkürzung: TM3

dominantes Allel: Sb^1

Genetik für Fortgeschrittene

Curly of Oster Balancer

Chromosom 2

Abkürzung: CyO

Dominantes Allel: Cy^1

Genetik für Fortgeschrittene

shibire Gen

shi^ts1, rezessiv

Dynamin Protein bindet nicht an Aktin –>Endozytose, Keimzellentwicklung, Lernen, Gedächtnis

Chromosom x

Genetik für Fortgeschrittene

decapentaplegic Gen

dpp, rezessiv

verändert Wachstumsregulation, Musterbildung, Apoptose, Zelldifferenzierung

Chromosom 2

Genetik für Fortgeschrittene

scalloped Gen

Sd^1, dominant

eingeschnittene Flügelränder

Chromosom x

Genetik für Fortgeschrittene

Welche Balancer gibt es und wo liegen sie?

CyO: Chromosom 2

TM2: Chromosom 3

TM3: Chromosom 3

TM6b: Chromosom 3

Gradient

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