Mol Pharma I at Universität Jena | Flashcards & Summaries

Lernmaterialien für Mol Pharma I an der Universität Jena

Greife auf kostenlose Karteikarten, Zusammenfassungen, Übungsaufgaben und Altklausuren für deinen Mol Pharma I Kurs an der Universität Jena zu.

TESTE DEIN WISSEN

what is a drug?

Lösung anzeigen
TESTE DEIN WISSEN

a chemical substance of known structure (other than a nutrient) that is administered to a living organism producing a biological effect

Lösung ausblenden
TESTE DEIN WISSEN

what is absorption?

Lösung anzeigen
TESTE DEIN WISSEN

this is when a drug reaches the blood circulation. Absorption occurs mostly in the small bowel.

Lösung ausblenden
TESTE DEIN WISSEN

what are the primary drug targets?

Lösung anzeigen
TESTE DEIN WISSEN

receptors
enzymes
carrier molecules (transporters)
ion channels

Lösung ausblenden
TESTE DEIN WISSEN

what is the difference between affinity and efficacy?

Lösung anzeigen
TESTE DEIN WISSEN

affinity is the tendency of a drug to bind to a receptor. efficacy is the tendency to activate the receptor once the drug is bound

Lösung ausblenden
TESTE DEIN WISSEN

what is Kd?

Lösung anzeigen
TESTE DEIN WISSEN

the concentration of free drug at which 50% of total receptors are occupied by a drug

Lösung ausblenden
TESTE DEIN WISSEN

what is the difference between Kd and EC50?

Lösung anzeigen
TESTE DEIN WISSEN

Kd referes to the affinity (binding) and 

EC50 refers to the efficacy

Lösung ausblenden
TESTE DEIN WISSEN

what are the steps in pharamacokientics?

Lösung anzeigen
TESTE DEIN WISSEN

absorption followed by distribution: storage , biotransformation or excretion

Lösung ausblenden
TESTE DEIN WISSEN

what is the difference between an agonist and an antagonist?

Lösung anzeigen
TESTE DEIN WISSEN

an agonist activates the receptor 

an antagonist blocks the receptor

Lösung ausblenden
TESTE DEIN WISSEN

what is the difference between a medicine and a poison

Lösung anzeigen
TESTE DEIN WISSEN

both are drugs. the medicine has a beneficial effect whilst the poison is harmful at a certain concentration

Lösung ausblenden
TESTE DEIN WISSEN

What is excretion?

Lösung anzeigen
TESTE DEIN WISSEN

this is the elimination of a drug or metabolite from the body through the kidneys (urine), bile (feces), or lung (respiration).

Lösung ausblenden
TESTE DEIN WISSEN

what is biotransformation?

Lösung anzeigen
TESTE DEIN WISSEN

this is the metabolization of the drug by enzymes (mostly CYP enzymes in the liver) into metabolites.

Lösung ausblenden
TESTE DEIN WISSEN

what are the routes of drug administration?

Lösung anzeigen
TESTE DEIN WISSEN

oral, sublingual, rectal, inhalation, injection, application to surface

Lösung ausblenden
  • 66617 Karteikarten
  • 1471 Studierende
  • 87 Lernmaterialien

Beispielhafte Karteikarten für deinen Mol Pharma I Kurs an der Universität Jena - von Kommilitonen auf StudySmarter erstellt!

Q:

what is a drug?

A:

a chemical substance of known structure (other than a nutrient) that is administered to a living organism producing a biological effect

Q:

what is absorption?

A:

this is when a drug reaches the blood circulation. Absorption occurs mostly in the small bowel.

Q:

what are the primary drug targets?

A:

receptors
enzymes
carrier molecules (transporters)
ion channels

Q:

what is the difference between affinity and efficacy?

A:

affinity is the tendency of a drug to bind to a receptor. efficacy is the tendency to activate the receptor once the drug is bound

Q:

what is Kd?

A:

the concentration of free drug at which 50% of total receptors are occupied by a drug

Mehr Karteikarten anzeigen
Q:

what is the difference between Kd and EC50?

A:

Kd referes to the affinity (binding) and 

EC50 refers to the efficacy

Q:

what are the steps in pharamacokientics?

A:

absorption followed by distribution: storage , biotransformation or excretion

Q:

what is the difference between an agonist and an antagonist?

A:

an agonist activates the receptor 

an antagonist blocks the receptor

Q:

what is the difference between a medicine and a poison

A:

both are drugs. the medicine has a beneficial effect whilst the poison is harmful at a certain concentration

Q:

What is excretion?

A:

this is the elimination of a drug or metabolite from the body through the kidneys (urine), bile (feces), or lung (respiration).

Q:

what is biotransformation?

A:

this is the metabolization of the drug by enzymes (mostly CYP enzymes in the liver) into metabolites.

Q:

what are the routes of drug administration?

A:

oral, sublingual, rectal, inhalation, injection, application to surface

Mol Pharma I

Erstelle und finde Lernmaterialien auf StudySmarter.

Greife kostenlos auf tausende geteilte Karteikarten, Zusammenfassungen, Altklausuren und mehr zu.

Jetzt loslegen

Das sind die beliebtesten StudySmarter Kurse für deinen Studiengang Mol Pharma I an der Universität Jena

Für deinen Studiengang Mol Pharma I an der Universität Jena gibt es bereits viele Kurse, die von deinen Kommilitonen auf StudySmarter erstellt wurden. Karteikarten, Zusammenfassungen, Altklausuren, Übungsaufgaben und mehr warten auf dich!

Die all-in-one Lernapp für Studierende

Greife auf Millionen geteilter Lernmaterialien der StudySmarter Community zu
Kostenlos anmelden Mol Pharma I
Erstelle Karteikarten und Zusammenfassungen mit den StudySmarter Tools
Kostenlos loslegen Mol Pharma I