Hormones 2019 at Universität Jena

Flashcards and summaries for Hormones 2019 at the Universität Jena

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Signal transduction to neighboring cells is called...?

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Signal transduction via bloodstream is called....?

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Signal transduction to own/clone cells is called...?
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Overview: flow of hormone Signaling?

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What is Cytochrome P450 important for?

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Why names Cytochrome P450 ?

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Cytochrom P450 mech?
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Exemplary flashcards for Hormones 2019 at the Universität Jena on StudySmarter:

Hormone Producing glands

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What are hormones?

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categories of cellular receptors (2) and their ligand

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Where are hormones generated?
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How do hormones reach their target?

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Exemplary flashcards for Hormones 2019 at the Universität Jena on StudySmarter:

Hormones 2019

Signal transduction to neighboring cells is called...?
Paracrine signaling

Hormones 2019

Signal transduction via bloodstream is called....?
endocrine signaling

Hormones 2019

Signal transduction to own/clone cells is called...?
Autocrine signaling

Hormones 2019

Overview: flow of hormone Signaling?
Biosynthesis -> storage, secretion -> transport -> recognition by rec -> relay & amplification of signal -> response -> (downregulation, neg feedback) -> breakdown

Hormones 2019

What is Cytochrome P450 important for?
drug metabolizing
making cholesterol, steroids, other important lipids

Hormones 2019

Why names Cytochrome P450 ?
membr bound, heme group, unusual absorption band at 450nm, P for pigment

Hormones 2019

Cytochrom P450 mech?
binds substrate RH > add electron (NADPH via adrenodoxin)> Fe3+ to Fe2+ > add O2 > bound at Fe2+ > electron via adrenodoxin > Fe3+OO2- and RH near > add 2H+ > H2O off, RH at Fe=O3+ > ROH leaves

Hormones 2019

Hormone Producing glands
pineal gland
hypothalamus
pituitary gland
(para)thyroid gland
thymus
adrenals
pancreas
ovaries and testes

Hormones 2019

What are hormones?
chemical mediators of signals

Hormones 2019

categories of cellular receptors (2) and their ligand
cell-surface/transmembrane receptor with hydropile ligand/hormone
nuclear/intercellular receptor with lipophilic lig

Hormones 2019

Where are hormones generated?
specialized cells, tissues

Hormones 2019

How do hormones reach their target?
via blood (endocrine signaling)

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