Infectous Diseases and Vaccines at Universität für Bodenkultur Wien

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Exemplary flashcards for Infectous Diseases and Vaccines at the Universität für Bodenkultur Wien on StudySmarter:

When did we manage to eradicate smallpox?

Exemplary flashcards for Infectous Diseases and Vaccines at the Universität für Bodenkultur Wien on StudySmarter:

Name 4 Classes of prokaryotic pathogens!

Exemplary flashcards for Infectous Diseases and Vaccines at the Universität für Bodenkultur Wien on StudySmarter:

How is a causative microorganism defined, according to the Henle Koch postulates?

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Exemplary flashcards for Infectous Diseases and Vaccines at the Universität für Bodenkultur Wien on StudySmarter:

Pathogenicity vs. Virulence

Exemplary flashcards for Infectous Diseases and Vaccines at the Universität für Bodenkultur Wien on StudySmarter:

Susceptibility vs. Disposition

Exemplary flashcards for Infectous Diseases and Vaccines at the Universität für Bodenkultur Wien on StudySmarter:

Minimum infective dose

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Colonization of bacteria. -> what means?

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Exemplary flashcards for Infectous Diseases and Vaccines at the Universität für Bodenkultur Wien on StudySmarter:

When can a colonizaiton of E.Coli on skin lead to an infeciton?

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What is pathogen toxicity?

Exemplary flashcards for Infectous Diseases and Vaccines at the Universität für Bodenkultur Wien on StudySmarter:

Name a few "resistance factors"!

Who has them?

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Epidemic vs. Endemic vs. Pandemic

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Mortality vs. Lethality

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Exemplary flashcards for Infectous Diseases and Vaccines at the Universität für Bodenkultur Wien on StudySmarter:

Infectous Diseases and Vaccines

When did we manage to eradicate smallpox?

1980

Infectous Diseases and Vaccines

Name 4 Classes of prokaryotic pathogens!

  • Chlamydiae
  • Rickettsiae
  • Mycoplasmas
  • Classic bacteria

Infectous Diseases and Vaccines

How is a causative microorganism defined, according to the Henle Koch postulates?

  1. Microbe must be found in the diseased individual
  2. It must be possible to cause the disease with pure cultures of the pathogen
  3. The pathogen may not just be an accompanying pathogen of another pathogen

Infectous Diseases and Vaccines

Pathogenicity vs. Virulence

An organism (species or strain) is defined as being pathogenic (or not), [-> fixed property of an organism/virus] and depending upon conditions, may exhibit different levels of virulence.


Also, a whole species (e.g. ) yersinia pestis is pathogenic(y/n.. in this case yes), while strains like y.p. orientalis or y.p. medievalis may be more pathogenic or less. -> species are considered pathogenic or not, while strains are considered more virulent or less.

Infectous Diseases and Vaccines

Susceptibility vs. Disposition

Susceptibility -> the probability of a certain species (humans, pigs) to get infected in general. Genetically determined.(e.g. humans are newly susceptible to some flu strains)


Disposition -> The probability of an individual to get infected at a certain timepoint, influenced by all kinds of factors. (in humans, immune system, sleep, feed status)

Infectous Diseases and Vaccines

Minimum infective dose

Smallest number of pathogen units required to cause an infection

Infectous Diseases and Vaccines

Colonization of bacteria. -> what means?

Microorganisms "colonize" commensally live on e.g. skin or mucosa on the human body, no penetration.

Infectous Diseases and Vaccines

When can a colonizaiton of E.Coli on skin lead to an infeciton?

When the pathogens somehow manage to enter the system by e.g. a cut in the skin, then are able to proliferate and the host reacts by e.g. redness and swelling.

Infectous Diseases and Vaccines

What is pathogen toxicity?

Is is a measure for the host tissue damage. -> e.g. Yersinia pestis -> highly toxic -> leads to large necrosis.

Infectous Diseases and Vaccines

Name a few "resistance factors"!

Who has them?

  • age
  • nutrition (how well fed)
  • climate
  • vaccination status
  • status of immune system
Not the pathogen, but the human!
Factors that decide, if a human will get sick after exposure to pathogen.

Infectous Diseases and Vaccines

Epidemic vs. Endemic vs. Pandemic

Epidemic: increase of infections, locally and timely restricted


Endemic: Prevalence of infections, locally restricted, but not in time -> long times


Pandemic: Increase in Infections, limited in time but not locally restricted

Infectous Diseases and Vaccines

Mortality vs. Lethality

Mortality: Probability to die of a certain disease: The number of deceased divided by the threatened population.

Lethality: Deaths per infected person *100 (e.g. 10%)

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