Beispielfragen Tumorbildung at Universität Bochum | Flashcards & Summaries

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Lernmaterialien für Beispielfragen Tumorbildung an der Universität Bochum

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How large is the portion of carcinomas compared to cancers in general?
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Approx. 80%
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What is myc? 
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myc is a transcription factor which regulates a lot of human genes. It enhances the transcription of the according genes. 
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What are the supposed outcomes when analysing a patient with MMR-deficient cancer? 
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- Normal (no cancer): Two PCR-bands (alleles of mother and father) 
- Chromosomal deletion: Just one band 
- MMR-deficiency: Lengths  variations different from normal DNA, but still two bands 
Lösung ausblenden
TESTE DEIN WISSEN
Identify the `tumorgenes´ which are according to the classical Tumor progression model involved in the sporadic colorectal carcinogenesis? 
Which of the following statements are correct?
A) p53
B) k-ras
C) Myc
D) Jum
E) BRCA2
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A) p53
B) k-ras
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Products of Porto-oncogenes are… 
Which of the following statements is wrong?
A) Growth factor receptors 
B) GTP-binding proteins
C) ATP syntethases
D) Tyrosine kinases 
E) DNA binding 
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C) ATP syntethases
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DNA can be found in humans as… 
Which of the following statements is wrong? 
A) Mitochondrial DNA 
B) Functionally important parts of ribosomal structure 
C) Highly repetitive DNA in the nucleus 
D) Insertions (introns) in genes 
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B) Functionally important parts of ribosomal structure 
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Products of ras genes typically bind to… 
Which of the following answers is correct? 
A) ADP
B) ATP
C) GMP 
D) GTP
E) UTP
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D) GTP
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The term of dysplasia describes the following histologisch changes… 
Which of the following statements is correct? 
A) Replacement of none differentiated type of tissue by another 
B) Increase in cell number within a tissue
C) Increase of cell size within a tissue 
D) Loss of tissue organization 
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D) Loss of tissue organization 
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The majority of malign tumors  are derivated from the following type of cells… 
Which of the following statements is correct? 
A) Stroma cells
B) Cells of the blood
C) Epithelial cells
D) Neuronal cells 
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C) Epithelial cells
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Which combination of terms is correct?
Which of the following statements is correct? 
A) Sarcoma - colon cancer
B) Leukemia - gastric cancer
C) Carcinoma - skin cancer 
D) Teratoma - cervical cancer
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TESTE DEIN WISSEN
C) Carcinoma - skin cancer 
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TESTE DEIN WISSEN
Which of the following statements are correct? 
RNA viruses…
A) Replicate episcopal (extrachromosomal)
B) Have to integrate their genomic info into the host genome 
C) Are unable to initiate tumors in general 
D) Are able to integrate cellular genes into their genome -> transformed into oncogenes 
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TESTE DEIN WISSEN
B) Have to integrate their genomic info into the host genome 
D) Are able to integrate cellular genes into their genome -> transformed into oncogenes 
Lösung ausblenden
TESTE DEIN WISSEN
Identify the correct age interval showing for the first time a significant rise in cancer incidence.
A) 50-60 years
B) 20-30 years
C) 30-40 years
D) 40-50 years
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TESTE DEIN WISSEN
A) 50-60 years
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Q:
How large is the portion of carcinomas compared to cancers in general?
A:
Approx. 80%
Q:
What is myc? 
A:
myc is a transcription factor which regulates a lot of human genes. It enhances the transcription of the according genes. 
Q:
What are the supposed outcomes when analysing a patient with MMR-deficient cancer? 
A:
- Normal (no cancer): Two PCR-bands (alleles of mother and father) 
- Chromosomal deletion: Just one band 
- MMR-deficiency: Lengths  variations different from normal DNA, but still two bands 
Q:
Identify the `tumorgenes´ which are according to the classical Tumor progression model involved in the sporadic colorectal carcinogenesis? 
Which of the following statements are correct?
A) p53
B) k-ras
C) Myc
D) Jum
E) BRCA2
A:
A) p53
B) k-ras
Q:
Products of Porto-oncogenes are… 
Which of the following statements is wrong?
A) Growth factor receptors 
B) GTP-binding proteins
C) ATP syntethases
D) Tyrosine kinases 
E) DNA binding 
A:
C) ATP syntethases
Mehr Karteikarten anzeigen
Q:
DNA can be found in humans as… 
Which of the following statements is wrong? 
A) Mitochondrial DNA 
B) Functionally important parts of ribosomal structure 
C) Highly repetitive DNA in the nucleus 
D) Insertions (introns) in genes 
A:
B) Functionally important parts of ribosomal structure 
Q:
Products of ras genes typically bind to… 
Which of the following answers is correct? 
A) ADP
B) ATP
C) GMP 
D) GTP
E) UTP
A:
D) GTP
Q:
The term of dysplasia describes the following histologisch changes… 
Which of the following statements is correct? 
A) Replacement of none differentiated type of tissue by another 
B) Increase in cell number within a tissue
C) Increase of cell size within a tissue 
D) Loss of tissue organization 
A:
D) Loss of tissue organization 
Q:
The majority of malign tumors  are derivated from the following type of cells… 
Which of the following statements is correct? 
A) Stroma cells
B) Cells of the blood
C) Epithelial cells
D) Neuronal cells 
A:
C) Epithelial cells
Q:
Which combination of terms is correct?
Which of the following statements is correct? 
A) Sarcoma - colon cancer
B) Leukemia - gastric cancer
C) Carcinoma - skin cancer 
D) Teratoma - cervical cancer
A:
C) Carcinoma - skin cancer 
Q:
Which of the following statements are correct? 
RNA viruses…
A) Replicate episcopal (extrachromosomal)
B) Have to integrate their genomic info into the host genome 
C) Are unable to initiate tumors in general 
D) Are able to integrate cellular genes into their genome -> transformed into oncogenes 
A:
B) Have to integrate their genomic info into the host genome 
D) Are able to integrate cellular genes into their genome -> transformed into oncogenes 
Q:
Identify the correct age interval showing for the first time a significant rise in cancer incidence.
A) 50-60 years
B) 20-30 years
C) 30-40 years
D) 40-50 years
A:
A) 50-60 years
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