Cancer at Springfield Technical Community College | Flashcards & Summaries

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Lernmaterialien für Cancer an der Springfield Technical Community College

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Characteristics of cancer cells 

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  • Loss of contact inhibition 
  • Proliferation occurs rapidly and cells grow in a pyramid effect 
  • Result from mutations of cellular genes 
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Grade IV

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Histology Grading 

  • Immature primitive (anaplasia
  • Undifferentiated (high grade)
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Carcinogens 

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Cancer-causing agents capable of producing cell alterations 

  • Many are detoxified and harmlessly excreted 
  • Failure of protective barriers allow them to enter and alter DNA 

Ex: Benzene, arsenic, formaldehyde

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Protooncogenes 
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Normal cell genes that are important regulators of normal cell processes 
  • Promote growth
  • When mutated they can function as oncogenes (tumor-inducing genes)
  • CEA- Carcinoembryonic Antigen 
  • FP a-fetoprotien
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Metastasis 

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Once tumor cells are free from primary tumor they travel to organs via 

  • Hematogenous
  • Lymphatic Routes  
  • Some cancers have an affinity for a particular tissue or organ
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CEA

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carcinoembryonic antigen

A substance that may be found in the blood of people who have colon cancer. CEA levels may help keep track of how well cancer treatments are working or if cancer has come back. It is a type of tumor marker.

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Sentinel Lymph Node 

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The first node confronted as tumor cells spread through the lymphatic system 

  • Biopsy can be done to determine extent of cancer 
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AFP 

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Has diagnostic value in liver cancer

  • Also produced when matastatic liver growth occurs 
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Grade I

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  • Cells differ slightly from normal cells (mild dysplasia) 
  • Well differentiated (low grade)
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Grade II

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Histology grading

  • More abnormal (moderate dysplasia) 
  • Moderately differentiated (intermediate grade)
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Oncogenes 
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Tumor inducing genes 

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Grade X

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Histology Grading 

  • Grade cannot be assessed 
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  • 863 Karteikarten
  • 14 Studierende
  • 0 Lernmaterialien

Beispielhafte Karteikarten für deinen Cancer Kurs an der Springfield Technical Community College - von Kommilitonen auf StudySmarter erstellt!

Q:

Characteristics of cancer cells 

A:
  • Loss of contact inhibition 
  • Proliferation occurs rapidly and cells grow in a pyramid effect 
  • Result from mutations of cellular genes 
Q:

Grade IV

A:

Histology Grading 

  • Immature primitive (anaplasia
  • Undifferentiated (high grade)
Q:

Carcinogens 

A:

Cancer-causing agents capable of producing cell alterations 

  • Many are detoxified and harmlessly excreted 
  • Failure of protective barriers allow them to enter and alter DNA 

Ex: Benzene, arsenic, formaldehyde

Q:
Protooncogenes 
A:
Normal cell genes that are important regulators of normal cell processes 
  • Promote growth
  • When mutated they can function as oncogenes (tumor-inducing genes)
  • CEA- Carcinoembryonic Antigen 
  • FP a-fetoprotien
Q:

Metastasis 

A:

Once tumor cells are free from primary tumor they travel to organs via 

  • Hematogenous
  • Lymphatic Routes  
  • Some cancers have an affinity for a particular tissue or organ
Mehr Karteikarten anzeigen
Q:

CEA

A:

carcinoembryonic antigen

A substance that may be found in the blood of people who have colon cancer. CEA levels may help keep track of how well cancer treatments are working or if cancer has come back. It is a type of tumor marker.

Q:

Sentinel Lymph Node 

A:

The first node confronted as tumor cells spread through the lymphatic system 

  • Biopsy can be done to determine extent of cancer 
Q:

AFP 

A:

Has diagnostic value in liver cancer

  • Also produced when matastatic liver growth occurs 
Q:

Grade I

A:
  • Cells differ slightly from normal cells (mild dysplasia) 
  • Well differentiated (low grade)
Q:

Grade II

A:

Histology grading

  • More abnormal (moderate dysplasia) 
  • Moderately differentiated (intermediate grade)
Q:
Oncogenes 
A:
Tumor inducing genes 

Q:

Grade X

A:

Histology Grading 

  • Grade cannot be assessed 
Cancer

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