INORGANIC CHEMISTRY at Sefako Makgatho Health Sciences University | Flashcards & Summaries

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TESTE DEIN WISSEN
thickeners
Lösung anzeigen
TESTE DEIN WISSEN
increase the viscosity of suspensions
Lösung ausblenden
TESTE DEIN WISSEN
what is the sedimentation volume 
Lösung anzeigen
TESTE DEIN WISSEN
the ratio of the unlimited/final volume of the sediment to the ratio of the original volume of the sediment [F=Vu/Vo]
Lösung ausblenden
TESTE DEIN WISSEN
what is the degree of flocculation(ß)
Lösung anzeigen
TESTE DEIN WISSEN
it is the ratio of the sedimentation volume of the flocculated suspension (F) to the sedimentation volume of the deflocculated suspension (Fo)

ß=F/Fo
Lösung ausblenden
TESTE DEIN WISSEN
brownian movement/motion
Lösung anzeigen
TESTE DEIN WISSEN
uncontrolled or erratic movement of particles in fluids due to their constant collision with other fast moving particles. 
Lösung ausblenden
TESTE DEIN WISSEN
difference between flocculated and deflocculated suspensions.
Lösung anzeigen
TESTE DEIN WISSEN
■deflocculated suspension 
•solids are present as individual particles 
•rate of sedimentation is low and particle size is small
•particles exhibit repulsive force
•pleasant appearance because of uniform dispersion of particles 
•particles settle independently 
•particles exist as separate entities 
•bioavailability is relatively high 

■flocculated suspension 
•solids aggregate by forming chemical bridges 
•slightly sediment and supernatant layer is formed 
•particles exhibit attractive force
•they settle as flocs
•rate is high as flocs are collection of small particles
•particles form loose aggregates
•bioavailability is comparatively low
Lösung ausblenden
TESTE DEIN WISSEN
formulation of suspensions
Lösung anzeigen
TESTE DEIN WISSEN
the formulation of suspension depends on whether the suspension is flocculated or deflocculated 

three commonly involved approaches 
1.Use of structured vehicles 
2.Use of controlled flocculations
3.Combination of both methods 
Lösung ausblenden
TESTE DEIN WISSEN
wetting agents
Lösung anzeigen
TESTE DEIN WISSEN
disperse solids in continuous liquid phase
Lösung ausblenden
TESTE DEIN WISSEN
flocculating agents
Lösung anzeigen
TESTE DEIN WISSEN
floc the drug particles 
Lösung ausblenden
TESTE DEIN WISSEN
buffers and pH adjusting agents
Lösung anzeigen
TESTE DEIN WISSEN
stabilize the suspension to a desired pH range
Lösung ausblenden
TESTE DEIN WISSEN
osmotic agents 
Lösung anzeigen
TESTE DEIN WISSEN
adjust osmotic pressure comparable to biological fluid
Lösung ausblenden
TESTE DEIN WISSEN
coloring agents 
Lösung anzeigen
TESTE DEIN WISSEN
impart desired colour to suspension and improve elegance 
Lösung ausblenden
TESTE DEIN WISSEN
preservatives 
Lösung anzeigen
TESTE DEIN WISSEN
prevent microbial growth
Lösung ausblenden
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Q:
thickeners
A:
increase the viscosity of suspensions
Q:
what is the sedimentation volume 
A:
the ratio of the unlimited/final volume of the sediment to the ratio of the original volume of the sediment [F=Vu/Vo]
Q:
what is the degree of flocculation(ß)
A:
it is the ratio of the sedimentation volume of the flocculated suspension (F) to the sedimentation volume of the deflocculated suspension (Fo)

ß=F/Fo
Q:
brownian movement/motion
A:
uncontrolled or erratic movement of particles in fluids due to their constant collision with other fast moving particles. 
Q:
difference between flocculated and deflocculated suspensions.
A:
■deflocculated suspension 
•solids are present as individual particles 
•rate of sedimentation is low and particle size is small
•particles exhibit repulsive force
•pleasant appearance because of uniform dispersion of particles 
•particles settle independently 
•particles exist as separate entities 
•bioavailability is relatively high 

■flocculated suspension 
•solids aggregate by forming chemical bridges 
•slightly sediment and supernatant layer is formed 
•particles exhibit attractive force
•they settle as flocs
•rate is high as flocs are collection of small particles
•particles form loose aggregates
•bioavailability is comparatively low
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Q:
formulation of suspensions
A:
the formulation of suspension depends on whether the suspension is flocculated or deflocculated 

three commonly involved approaches 
1.Use of structured vehicles 
2.Use of controlled flocculations
3.Combination of both methods 
Q:
wetting agents
A:
disperse solids in continuous liquid phase
Q:
flocculating agents
A:
floc the drug particles 
Q:
buffers and pH adjusting agents
A:
stabilize the suspension to a desired pH range
Q:
osmotic agents 
A:
adjust osmotic pressure comparable to biological fluid
Q:
coloring agents 
A:
impart desired colour to suspension and improve elegance 
Q:
preservatives 
A:
prevent microbial growth
INORGANIC CHEMISTRY

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