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What did Levene discover about DNA?
DNA is a polymer of nucleotides and each nucleotide consists of deoxyribose sugar, phosphate, nitrogen-containing base
What is the nitrogen-containing bases?
Adenine, guanine, cytosine, thymine
What is the difference between purine and pyrimidine?
Purine- 2 carbon-nitrogen ring bases
Pyrimidine- one carbon
What did Erwin Chargaff do?
He analyzed the base composition of DNA from different species
What did Rosalind Franklin do?
She was an x-ray crystallographer
DNA is a helix
diameter is 2nm
a complete turn of the helix every 3.4 nm
DNA is 2 strands held together by....
Hydrogen bonds between bases
What carries the genetic information in DNA?
Sequence of base pairs
Semiconservative DNA replication
The new DNA consists of 1 "old" strand and 1 "new" strand
The pre-replication complex binds to....
the origin of replication
How does replication occur?
the addition of new nucleotides to the 3' OH of an existing nucleotide
What does DNA polymerase III add to primer?
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