Kays- Superficial And Invasive Fungal Infections at Purdue University | Flashcards & Summaries

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what is the preferred empiric treatment of suspected invasive candidiasis in ICU (nonneutropenic adults)?

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echinocandin

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what is the primary line of host defenses against superficial Candida infections (oropharyngeal & esophageal)?

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cell-mediated immunity

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what is the duration of therapy for esophageal candidiasis?

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14-21 days

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when is systemic therapy needed for treatment of OPC?

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refractory OPC

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what is the duration of therapy for OPC?

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7-14 days

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what is the duration of therapy for fluconazole-refractory OPC?

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>/= 14 days (up to 28 days)

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select all of the following treatment options for MILD OPC?

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clotrimazole 10 mg troche

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what is the duration of treatment for fluconazole-refractory esophageal candidiasis?

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21-28 days

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is this uncomplicated or complicated vulvovaginal candidiasis?


"sporadic infection that is susceptible to all forms of antifungal therapy regardless of treatment duration"

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uncomplicated

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is this uncomplicated or complicated vulvovaginal candidiasis?


"recurrent VVC; severe disease; non-Candida ablicans infection; host factors (DM, immunosuppression, pregnancy)"

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complicated

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select all of the following that are systemic treatment options for OPC?

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fluconazole

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treatment of OPC - general approach

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  • treatment of OPC should be individualized
    • underlying immune status
    • concurrent mucosal and medical diseases
    • concomitant medications
    • exogenous infectious sources
  • minimize predisposing factors
  • institute proper oral hygiene
  • treatment options: drug adherence, adequate saliva for dissolution of solid topical medications, drug interactions, location and severity of infection
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Beispielhafte Karteikarten für deinen kays- superficial and invasive fungal infections Kurs an der Purdue University - von Kommilitonen auf StudySmarter erstellt!

Q:

what is the preferred empiric treatment of suspected invasive candidiasis in ICU (nonneutropenic adults)?

A:

echinocandin

Q:

what is the primary line of host defenses against superficial Candida infections (oropharyngeal & esophageal)?

A:

cell-mediated immunity

Q:

what is the duration of therapy for esophageal candidiasis?

A:

14-21 days

Q:

when is systemic therapy needed for treatment of OPC?

A:

refractory OPC

Q:

what is the duration of therapy for OPC?

A:

7-14 days

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Q:

what is the duration of therapy for fluconazole-refractory OPC?

A:

>/= 14 days (up to 28 days)

Q:

select all of the following treatment options for MILD OPC?

A:

clotrimazole 10 mg troche

Q:

what is the duration of treatment for fluconazole-refractory esophageal candidiasis?

A:

21-28 days

Q:

is this uncomplicated or complicated vulvovaginal candidiasis?


"sporadic infection that is susceptible to all forms of antifungal therapy regardless of treatment duration"

A:

uncomplicated

Q:

is this uncomplicated or complicated vulvovaginal candidiasis?


"recurrent VVC; severe disease; non-Candida ablicans infection; host factors (DM, immunosuppression, pregnancy)"

A:

complicated

Q:

select all of the following that are systemic treatment options for OPC?

A:

fluconazole

Q:

treatment of OPC - general approach

A:
  • treatment of OPC should be individualized
    • underlying immune status
    • concurrent mucosal and medical diseases
    • concomitant medications
    • exogenous infectious sources
  • minimize predisposing factors
  • institute proper oral hygiene
  • treatment options: drug adherence, adequate saliva for dissolution of solid topical medications, drug interactions, location and severity of infection
kays- superficial and invasive fungal infections

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