Gregg Final Review at Nova Southeastern University Dr. Kiran C. Patel College Of Osteopathic Medicine | Flashcards & Summaries

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The following disease has this transmission route. What will most likely be seen? R – muscle, V – dorsal root ganglia, R – dorsal root ganglia, V – along nerves to tissues (brain, kidney, salivary glands etc.) 

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negri bodies

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Naked virus _____ Enveloped _____

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gut, respiratory

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The following pathogenesis describes what virus?

  • Replication in regional LN, viremia to liver & spleen (mononuclear cell replication), cellular viremia to skin, replication in keratinocytes fibroblasts & others, retrograde axonal flow dorsal ganglia latency for later reinfection possible once waning immunity
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VZV

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For HPV, What occurs at the spinosum layer? At the granulosum layer?

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Granulosum is where E6 & E7 are released to cause cell proliferation

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A maculopapule coalescence forming blotches that turn dark brown & peel off on the skin has what pathogenesis?

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  • Replication upper respiratory epithelial cells, viremia lymphoid tissues, bone marrow, skin, respiratory tract, abdominal organs WBC
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What type of virus is the following disease? 

  • Replication local endothelial cells & erythrocytes, viremia bone marrow and other blood cells, viral replication lyse red cells & in Bone marrow which can interrupt RBC production
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Naked ssDNA

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HPV-16 & HPV-18 cause cancer how?

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  • From S. granulosum layer, HPV creates E6 that blocks action of p53 & E7 that prevents Rb action leading to cell cycle without check or repair so easy mutation chance
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For Hepatitis B, The acute disease is detected by ______, and acute disease resolution has ________. Chronic persistence shows _______ due to a lack of ______ to clear the disease.

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TESTE DEIN WISSEN
  1. HbsAg, HBeAg, Anti-HBcAg IgM
  2. Anti-HbsAg or anti HBcAg (IgG)
  3. HbsAg
  4. Anti HBs-Ag IgG
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Parotitis is seen in a patient. What is the pathogenesis?

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  • Replication start in nasal/upper respiratory tract, Viremia to salivary glands then other organs (spleen, peripheral lymph)
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Which of the following are transmitted primarily through inhaled respiratory droplets?

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Mumps Rubulavirus

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TESTE DEIN WISSEN

Clay colored stool, darkening urine, and jaundice are all signs of a

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Enveloped partially dsDNA

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What is the pathogenesis of the following virus? Viral infection of B cells nonproductive but targets receptor 2 and then epithelial CD21. Infected nonproductive cells immortalized via LMP1 viral growth factor for uncontrolled proliferation

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TESTE DEIN WISSEN
  • Primary infection initiates in oropharynx (nasopharynx same), replication in pharynx & salivary glands with immortalized B cells making heterophile antibody, cellular viremia to other sites via circulating B cells most eliminated by CD8+ T cell response
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Beispielhafte Karteikarten für deinen Gregg Final Review Kurs an der Nova Southeastern University Dr. Kiran C. Patel College Of Osteopathic Medicine - von Kommilitonen auf StudySmarter erstellt!

Q:

The following disease has this transmission route. What will most likely be seen? R – muscle, V – dorsal root ganglia, R – dorsal root ganglia, V – along nerves to tissues (brain, kidney, salivary glands etc.) 

A:

negri bodies

Q:

Naked virus _____ Enveloped _____

A:

gut, respiratory

Q:

The following pathogenesis describes what virus?

  • Replication in regional LN, viremia to liver & spleen (mononuclear cell replication), cellular viremia to skin, replication in keratinocytes fibroblasts & others, retrograde axonal flow dorsal ganglia latency for later reinfection possible once waning immunity
A:

VZV

Q:

For HPV, What occurs at the spinosum layer? At the granulosum layer?

A:

Granulosum is where E6 & E7 are released to cause cell proliferation

Q:

A maculopapule coalescence forming blotches that turn dark brown & peel off on the skin has what pathogenesis?

A:
  • Replication upper respiratory epithelial cells, viremia lymphoid tissues, bone marrow, skin, respiratory tract, abdominal organs WBC
Mehr Karteikarten anzeigen
Q:

What type of virus is the following disease? 

  • Replication local endothelial cells & erythrocytes, viremia bone marrow and other blood cells, viral replication lyse red cells & in Bone marrow which can interrupt RBC production
A:

Naked ssDNA

Q:

HPV-16 & HPV-18 cause cancer how?

A:
  • From S. granulosum layer, HPV creates E6 that blocks action of p53 & E7 that prevents Rb action leading to cell cycle without check or repair so easy mutation chance
Q:

For Hepatitis B, The acute disease is detected by ______, and acute disease resolution has ________. Chronic persistence shows _______ due to a lack of ______ to clear the disease.

A:
  1. HbsAg, HBeAg, Anti-HBcAg IgM
  2. Anti-HbsAg or anti HBcAg (IgG)
  3. HbsAg
  4. Anti HBs-Ag IgG
Q:

Parotitis is seen in a patient. What is the pathogenesis?

A:
  • Replication start in nasal/upper respiratory tract, Viremia to salivary glands then other organs (spleen, peripheral lymph)
Q:

Which of the following are transmitted primarily through inhaled respiratory droplets?

A:

Mumps Rubulavirus

Q:

Clay colored stool, darkening urine, and jaundice are all signs of a

A:

Enveloped partially dsDNA

Q:

What is the pathogenesis of the following virus? Viral infection of B cells nonproductive but targets receptor 2 and then epithelial CD21. Infected nonproductive cells immortalized via LMP1 viral growth factor for uncontrolled proliferation

A:
  • Primary infection initiates in oropharynx (nasopharynx same), replication in pharynx & salivary glands with immortalized B cells making heterophile antibody, cellular viremia to other sites via circulating B cells most eliminated by CD8+ T cell response
Gregg Final Review

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