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_____ cells are also located on the muscle's cells surface on shallow depressions. describe these cells?
satellite cells/myogenic stem cells
regenerative cells
what are t tubules?
skeletal muscle membrane is that it is continued within the skeletal muscle fiber as numerous long, tubular invaginations resembling tunnels that intertwine among the myofibrils called T tubules
location of T/transverse tubules?
plane of the junction of the A and I bands
what is a triad in the muscle? main function?
T tubule flanked by 2 terminal cisternae of sarcoplasmic reticulum
allows depolarization wave to spread
myofibrils are held in register with one another by __________ intermediate filament?
desmin-postnatal
vimentin-embryo
how is desmin attached to the Z lines of sarcomeres?
plectin
which protein ensures the protection of the bond between desmin and the Z line?
αβ- crystallin
what are costameres?
The peripheral-most bundles of myofibrils located just adjacent to the sarcolemma are tethered by desmin
of the sarcolemma, filaments to specific locations on the cytoplasmic aspect known as costameres
costameres are rich in which protein complex?
dystrophin-associated glycoprotein complex
proteins in dystrophin-associated glycoprotein complex?
dystrophin, dystroglycan complex, sarcoglycan complex, dystrobrevin, syntrophin
describe dystrophin and its attachments. its function?
what kind of tissue forms epimysium, perimysium and endomysium?
epi-dense irregular collagenous tissue
peri-less dense collagenous connective tissue derived from epimysium
endo-reticular fibers and external lamina/basal lamina
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