Physikum at LMU München

Flashcards and summaries for Physikum at the LMU München

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Myasthenia gravis

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Botox

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Tetanus- Toxin

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Nicht depolarisierende Muskelrelaxanten

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Kreatinsynthese

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Maltose

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Lactose

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Saccharose

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Cellulose


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Welche AS enthält einen Heterozyklus

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Welche AS hat ein Thiol

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Duftwahrnehmungsequenz

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Exemplary flashcards for Physikum at the LMU München on StudySmarter:

Physikum

Myasthenia gravis

  • Autoimmunerkrankung
  • AK gegen Strukturen der motorischen Endplatte/AK gegen ACh-R


keine EPSP-->belastungsabhängige Schwäche

Physikum

Botox

Spaltet SNAP-25/ Synaptobrevin--> Hemmung der ACh- Freisetzung in den subsynaptischen Spalt--> Muskellähmung

Physikum

Tetanus- Toxin

Spaltet Synaptobrevin in Interneurone--> keine Gylcin-Freisetzung--> Enthemmung alpha-Motoneurone--> erhöhung der Impulsfrequenz--> Krämpfe

Physikum

Nicht depolarisierende Muskelrelaxanten

Beispiel: Curare

Kompetitive Antagonisten am ACh-R--> keine Depolarisation

Physikum

Kreatinsynthese

1.Schritt: in der Niere

Arginin + Glycin--> Ornithin + Guanidinoacetat

Enzm: Arginin-Glycin-Amidinotransferase


2. Schritt: In der Leber

Methylierung von Guanidinoacetat zu Kreatinin

Physikum

Maltose

2x Glucose

A 1-4

Physikum

Lactose

1x Glucose

1x Galaktose


B 1-4

Physikum

Saccharose

1x Glucose

1xFructose

A 1--> B2

Physikum

Cellulose


B 1-4

Physikum

Welche AS enthält einen Heterozyklus

Histidin

Physikum

Welche AS hat ein Thiol

Cystein

Physikum

Duftwahrnehmungsequenz

 Duftstoff bindet an die Bindetasche des Rezeptors → Aktivierung des G-Proteins → Aktivierung einer Adenylatcyclase →  ATP wird zum cAMP → cAMP bindet an die cAMP-gesteuerten Ionenkanäle (sog. „CNG-Kanäle“ ) der Zilienmembran → Öffnung der CNG-Kanäle → Einstrom von Na+- und Ca2+→ Depolarisation → Durch einströmendes Calcium Öffnung von Ca2+-gesteuerten Chloridkanälen → Ausstrom von Cl− → Verstärkung der Depolarisation → Weiterleitung der Aktionspotentiale über die Axone (N. olfactorius) zum Bulbus ol

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