General Pathology at LMU München

=Intravascular mass circulating and obstructing blood/lymphatic vessels

→ Thrombus particles, Fat embolisms (from bone fracture, can be found in lung later due to them being in veins), Air embolism (iatrogen, chest wall injuries), Amniotic fluid embolism (parturition complications), Tumor cells, Fibro-cartilage parts (disc injury), Parasites/Bacteria

→ Can lead to bacterial endocarditis, Infarction of the kidney etc.

Therapy/ Prevention :
Aspirin → inhibits platelet aggregation, blocks AA metabolite (thromboxane)

lower body temperature (ears-skin-head-extremities-viscera)

clear fluid in alveolar lumen

Reduced tissue blood flow/ perfusion → low o2, low nutrients, accumulation of metabolites (ischaemic core is necrotic, ischemic penumbra (if partial occlusion surrounds it)

Arterial Thrombus - White, 

Venous Thrombus -Red

o2 on erys decreased (acute/chronic)

Cardiac/Respiratory arrest, Areflexia, Brain (3-5 min), Heart (30 min), Conn. tissue (hours)

Process of death

when disease in one organ makes it worse for the same organ in circle

-> Heart (Artial/Ventricular dilation esp. right side)
-> Lungs (Congestion-red colour, Pulmonary edema-alveolar fluid, Emphysema-alveolar rupture, increased air in alveoli)
->Other organs (Congestion, Anemia)

->Early: Algor/Rigor mortis, mucous drying, blood clotting, staining (imbibition), autolysis
->Late: Putrefaction (pseudomelanosis, bloating), skeletonization, mummification, maceration

Agonal, Incidental, Disease associated, Postmortal, Euthansia artefacts