General Pathology at LMU München

Flashcards and summaries for General Pathology at the LMU München

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Embolus

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Algor mortis

Exemplary flashcards for General Pathology at the LMU München on StudySmarter:

Pulmonary edema

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Ischemia

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Thrombus type

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Anemia

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Clinical death

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Thanatogensis

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Vicious circle

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Agonal changes

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Postmortal changes

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True/pathological changes post mortem 

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Exemplary flashcards for General Pathology at the LMU München on StudySmarter:

General Pathology

Embolus

=Intravascular mass circulating and obstructing blood/lymphatic vessels


→ Thrombus particles, Fat embolisms (from bone fracture, can be found in lung later due to them being in veins), Air embolism (iatrogen, chest wall injuries), Amniotic fluid embolism (parturition complications), Tumor cells, Fibro-cartilage parts (disc injury), Parasites/Bacteria

→ Can lead to bacterial endocarditis, Infarction of the kidney etc.

Therapy/ Prevention :
Aspirin → inhibits platelet aggregation, blocks AA metabolite (thromboxane)

General Pathology

Algor mortis

lower body temperature (ears-skin-head-extremities-viscera)

General Pathology

Pulmonary edema

clear fluid in alveolar lumen

General Pathology

Ischemia

Reduced tissue blood flow/ perfusion → low o2, low nutrients, accumulation of metabolites (ischaemic core is necrotic, ischemic penumbra (if partial occlusion surrounds it)

General Pathology

Thrombus type

Arterial Thrombus - White, 

Venous Thrombus -Red

General Pathology

Anemia

o2 on erys decreased (acute/chronic)

General Pathology

Clinical death

Cardiac/Respiratory arrest, Areflexia, Brain (3-5 min), Heart (30 min), Conn. tissue (hours)

General Pathology

Thanatogensis

Process of death

General Pathology

Vicious circle

when disease in one organ makes it worse for the same organ in circle

General Pathology

Agonal changes

-> Heart (Artial/Ventricular dilation esp. right side)
-> Lungs (Congestion-red colour, Pulmonary edema-alveolar fluid, Emphysema-alveolar rupture, increased air in alveoli)
->Other organs (Congestion, Anemia)

General Pathology

Postmortal changes

->Early: Algor/Rigor mortis, mucous drying, blood clotting, staining (imbibition), autolysis
->Late: Putrefaction (pseudomelanosis, bloating), skeletonization, mummification, maceration

General Pathology

True/pathological changes post mortem 

Agonal, Incidental, Disease associated, Postmortal, Euthansia artefacts


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