Immunology - Immunological memory and vaccination at Hochschule Bonn-Rhein-Sieg

Flashcards and summaries for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg

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Study with flashcards and summaries for the course Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg

Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Which beneficial characteristics should vaccines show?

Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Who carried out the first vaccination and how?

Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Who was the next important person in the immunology?

Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What does a good vaccination rely on?

Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are the three categories memory T cells can be devided?

Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are the functions of central memory T cells?

Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are the functions of effector memory T cells?

Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Which are the four main goals that should be achieved (talking about vaccination)?

Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is herd immunity?

Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Explain passive immunization.

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Explain active immunization.

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What type of pathogens are used in attenuated vaccination?

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Exemplary flashcards for Immunology - Immunological memory and vaccination at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Immunology - Immunological memory and vaccination

Which beneficial characteristics should vaccines show?
  • cheap
  • long immunity
  • few as possible side effects
  • safe and efficient application
  • effective adaptive immune system activation
  • stable storage

Immunology - Immunological memory and vaccination

Who carried out the first vaccination and how?
  • Edward Jenner
  • vaccination against small pox

Immunology - Immunological memory and vaccination

Who was the next important person in the immunology?
  • Louis Pasteur
  • against cholera and rabies

Immunology - Immunological memory and vaccination

What does a good vaccination rely on?

Solid activation of B and T cells.

Immunology - Immunological memory and vaccination

What are the three categories memory T cells can be devided?

  1. TCM (central memory T cell)
  2. TEM (effector memory Tcell)
  3. TRM (resident memory Tcell)

Immunology - Immunological memory and vaccination

What are the functions of central memory T cells?
  • foundi n lymphoid tissue (high proliferation capacity)
  • highly sensitive
  • often not found at site of infectionn
  • restricted to spleen and lymph nodes

Immunology - Immunological memory and vaccination

What are the functions of effector memory T cells?
  • commonly found in blood and other non-lymphoid tissue
  • react quick
  • show high production of effector cytokines

Immunology - Immunological memory and vaccination

Which are the four main goals that should be achieved (talking about vaccination)?
  1. lymphocytes should be primed and become memory cells
  2. antigen should be as harmless as possible
  3. adjuvants can be used for immune reaction boost
  4. production of vaccines should be safe and affordable

Immunology - Immunological memory and vaccination

What is herd immunity?
  • Principle of 95% of the population should be vaccinated
  • allows those are medically exempt to remain protected as well

Immunology - Immunological memory and vaccination

Explain passive immunization.
  • specific antibodies are given to fight pathogens/toxins in the blood
  • preventative treatment
  • works fast
  • can be used on immunodeficient patients
  • expensive
  • must be applied intravenously

Immunology - Immunological memory and vaccination

Explain active immunization.
  • induces effective activation of adaptive immune system
  • activation of memory cells
  • makes secondary response easier
  • pathogen/toxins are recognized quicker and more effective
  • DIfferentiated again: 1. living/attenuated organisms and 2. inactivated/killed organisms

Immunology - Immunological memory and vaccination

What type of pathogens are used in attenuated vaccination?
weakend pathogens which are heavilz reduced in their virulence

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