Immunology - Immunity to Viruses at Hochschule Bonn-Rhein-Sieg

Flashcards and summaries for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg

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Study with flashcards and summaries for the course Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is responsible for type 1 response?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is the only effective molecule against viruses?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is responsible for type 2 response?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What happens in the first line response of viruses?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is responsible for the second line defense (innate system)?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Which receptor do recognize PAMPs?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Which cells are included in second line defense?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is the main function of macrophage M1?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What kind of cytokines does M1 produce?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

RIG-I--like receptors and MDA 5 are found in the cytoplasm. What do they recognize?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What does cGAS-Sting recognize in the cytosol?

Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What does the endosomal TLRs (3,7,9) recognize?

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Exemplary flashcards for Immunology - Immunity to Viruses at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Immunology - Immunity to Viruses

What is responsible for type 1 response?
  • NK cells
  • ILC-1
  • TH1
  • CTL
  • Macrophages

Immunology - Immunity to Viruses

What is the only effective molecule against viruses?
Collectins

Immunology - Immunity to Viruses

What is responsible for type 2 response?
  • NK cells
  • ILCs
  • DCs
  • Macrophages

Immunology - Immunity to Viruses

What happens in the first line response of viruses?
Physical and chemical barrier:
Mucus, cilia, skin
pH, fatty acid
Proteolytic enymes, lysosyme/defensins
Intestinal enzyme, bile

Immunology - Immunity to Viruses

What is responsible for the second line defense (innate system)?

  • NK cells
  • ILCs
  • Macrophages
  • DC

Immunology - Immunity to Viruses

Which receptor do recognize PAMPs?
  • NOD-like receptor
  • RIG-I-like receptors
  • membrane bound TLRs

Immunology - Immunity to Viruses

Which cells are included in second line defense?
  • NK cells
  • ILCs
  • DCs
  • Macrophages

Immunology - Immunity to Viruses

What is the main function of macrophage M1?
Phagocytose virus particles and kill virally infected cells


Immunology - Immunity to Viruses

What kind of cytokines does M1 produce?
  • Type 1 interferons
  • TNF alpha
  • Nitric oxide

Immunology - Immunity to Viruses

RIG-I--like receptors and MDA 5 are found in the cytoplasm. What do they recognize?
  • ssRNA
  • dsRNA

Immunology - Immunity to Viruses

What does cGAS-Sting recognize in the cytosol?
cytosolic DNA

Immunology - Immunity to Viruses

What does the endosomal TLRs (3,7,9) recognize?
phagocytosed (extracellular) viral RNA and DNA

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