Immunology: B-cell Activation and Secondary Lymphoid Organs at Hochschule Bonn-Rhein-Sieg

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Study with flashcards and summaries for the course Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Where are T-cells activated?

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Where are B-cells activated? 

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Where are follicles/B-cell zones present? 

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

From where do lymph nodes filter/collect antigens? 

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

From where does spleen filter/collect antigens? 

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

From where does MALT filter/collect antigens?

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Which criteria have to be met by the secondary lymphoid organs to activate B-/T-cells?

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

In the lymph node, the follicle can be divided into how many parts? Which ones and what do they contain? 

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

The secondary follicle of the lymph node is subdivided into three parts. Which ones and what do they contain? 

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

How is the spleen subdivided and what are the different parts responsible for? 

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

How are naive B- and T-cells carried through the white pulp

Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Where are B-cells found in the spleen? Where are T-cells found in the spleen? 

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Exemplary flashcards for Immunology: B-cell Activation and Secondary Lymphoid Organs at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Immunology: B-cell Activation and Secondary Lymphoid Organs

Where are T-cells activated?
in the T-cell zone

Immunology: B-cell Activation and Secondary Lymphoid Organs

Where are B-cells activated? 
In follicles/B-cell zones

Immunology: B-cell Activation and Secondary Lymphoid Organs

Where are follicles/B-cell zones present? 
In all secondary lymphoid organs 

Immunology: B-cell Activation and Secondary Lymphoid Organs

From where do lymph nodes filter/collect antigens? 
From tissues throughout the body

Immunology: B-cell Activation and Secondary Lymphoid Organs

From where does spleen filter/collect antigens? 
from the blood 

Immunology: B-cell Activation and Secondary Lymphoid Organs

From where does MALT filter/collect antigens?
from the mucosal surface

Immunology: B-cell Activation and Secondary Lymphoid Organs

Which criteria have to be met by the secondary lymphoid organs to activate B-/T-cells?
1. allow entry of antigen

2. allow entry of naive B- and T-cells through HEV

3. must have areas for interactions between B- and T-cells

4. must allow effector (mature) cells and their molecules (e.g. antibodies) to exit

Immunology: B-cell Activation and Secondary Lymphoid Organs

In the lymph node, the follicle can be divided into how many parts? Which ones and what do they contain? 
1. primary follicles (contain only naive B-cells)

2. secondary follicles (contain both mature and naive B-cells)

Immunology: B-cell Activation and Secondary Lymphoid Organs

The secondary follicle of the lymph node is subdivided into three parts. Which ones and what do they contain? 
1. Germinal center (contains cluster of active B-cells)

2. Corona (contains naive B-cells that migrate to germinal center once activated)

3. Paracortex (contains T-cell areas and APCs alongside the HEV)

Immunology: B-cell Activation and Secondary Lymphoid Organs

How is the spleen subdivided and what are the different parts responsible for? 
1. Red pulp (responsible for filtering old blood cells)

2. White pulp (responsible for T- and B-cell activation) 

Immunology: B-cell Activation and Secondary Lymphoid Organs

How are naive B- and T-cells carried through the white pulp
by blood vessels

Immunology: B-cell Activation and Secondary Lymphoid Organs

Where are B-cells found in the spleen? Where are T-cells found in the spleen? 
B-cells: In follicles 

T-cells: in Peri-arteriolar lymphoid sheath (PALS) 

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