Dev Bio Gene Expression at Hochschule Bonn-Rhein-Sieg

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Tracing of cell lineages is used to create

fate maps

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How to trace cell lineages

Direct Observation of embryo

Dye marking

Genetic labbeling

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Genetic labbeling

permanent labbeling of cells and their progressors

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Chimera

Individual containing cells from two different species

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Genomic equivalence

Each somatic cell nucleus within an organism has identical chromosomes and same set of genes

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nucleosomes can be wound into tight

solenoids

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Heterochromation

Chromatin mainly in solenoid conformation, low transcription rate

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Acetylation

compensates positive charge of lysines and loosens nucleosomes

activation of transcription

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Methylation

can repress or activate

mainly repress

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Enhancer

DNA sequence which controls efficency and rate of transcription

binds transcription factors

Can control temporal and tissue specific expression of genes

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Enhancers are cis regulatory elements

only activate Promotor on same chromosome

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Transcription factor domains

DNA binding domain

Trans activation domain

Protein-protein interaction domain

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Dev Bio Gene expression at Hochschule Bonn-Rhein-Sieg

Flashcards and summaries for Dev Bio Gene expression at the Hochschule Bonn-Rhein-Sieg

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