DB Chapter 5: Cell signaling at Hochschule Bonn-Rhein-Sieg

Flashcards and summaries for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg

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Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Cell movement in particular directions to specific locations is important in ___________.

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Mention the 5 steps of cell migration!

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is polarization (cell migration) directed by? 

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is protrusion of the leading edge managed by? 

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Which proteins are responsible for focal adhesion the the extracellular matrix? 

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is release of focal adhesion controlled by? 

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is "EMT" and what does it involve? 

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Where is EMT involved in? 

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What does "cell signaling" mean?

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are inducers regarding cell signaling? 

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Inducer signals are often _________

Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is a responder regarding cell signaling?

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Exemplary flashcards for DB Chapter 5: Cell signaling at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

DB Chapter 5: Cell signaling

Cell movement in particular directions to specific locations is important in ___________.

tissue formation during embryonic development

DB Chapter 5: Cell signaling

Mention the 5 steps of cell migration!

1. Polarisation 

2. Protrusion of the leading edge 

3. Focal adhesion to the extracellular matrix 

4. Movement along the actin filaments

5. Release of focal adhesions

DB Chapter 5: Cell signaling

What is polarization (cell migration) directed by? 

It is directed by diffusing signals or the extracellular matrix

DB Chapter 5: Cell signaling

What is protrusion of the leading edge managed by? 

It is managed by actin filaments

DB Chapter 5: Cell signaling

Which proteins are responsible for focal adhesion the the extracellular matrix? 

Integrin proteins in the cell membrane are responsible. 

DB Chapter 5: Cell signaling

What is release of focal adhesion controlled by? 

It is controlled by calcium

DB Chapter 5: Cell signaling

What is "EMT" and what does it involve? 

EMT = epithelial-mesenchymal transition 


involves:

  • downregulation of cadherins
  • loss of attachment to basement membrane 
  • rearrangement of cytoskeleton
  • secretion of new extracellular matrix molecules

DB Chapter 5: Cell signaling

Where is EMT involved in? 

Formation of neural crest 

DB Chapter 5: Cell signaling

What does "cell signaling" mean?

Communication between cells during induction.

DB Chapter 5: Cell signaling

What are inducers regarding cell signaling? 

Inducers are tissue, that produce a signal that changes the behavior of another tissue.

DB Chapter 5: Cell signaling

Inducer signals are often _________

autocrine factors.

DB Chapter 5: Cell signaling

What is a responder regarding cell signaling?

A responder is the tissue that is induced

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