DB Chapter 1: Introduction at Hochschule Bonn-Rhein-Sieg

Flashcards and summaries for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg

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Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

How many clearly distinguishable cell types does the human body have? 

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What is the reason for premature stop of cell division in limb cartilage precursor cells?

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Define "fertilization".

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Define "cleavage". 

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Define "gastrulation". What happens there? 

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Define "Organogenesis". With what does it start? 

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Define "Malformation". 

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

Define "Disruption".

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are examples for teratogens

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are advantages of the sea urchin as a model organism for study of development? 

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are the main topics of developmental biology?

Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

What are advantages for the nematode (caenorhbditis elegans) as a model organism for study of development?

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Exemplary flashcards for DB Chapter 1: Introduction at the Hochschule Bonn-Rhein-Sieg on StudySmarter:

DB Chapter 1: Introduction

How many clearly distinguishable cell types does the human body have? 

> 250

DB Chapter 1: Introduction

What is the reason for premature stop of cell division in limb cartilage precursor cells?

An extra copy of the Fgf4 gene. 

DB Chapter 1: Introduction

Define "fertilization".

= Merging of the haploid nuclei of sperm and egg, which is followed by cytoplasmic movements and determination of by axes.

DB Chapter 1: Introduction

Define "cleavage". 

= First series of rapid mitotic divisions

DB Chapter 1: Introduction

Define "gastrulation". What happens there? 

Gastrulation is the formation of the gastrula.


What happens:

- Drastic cell movements

- Rearrangement of embryo

- Formation of germ layers (ectoderm, endoderm, mesoderm) 

DB Chapter 1: Introduction

Define "Organogenesis". With what does it start? 

Organogenesis is the formation of organs out of the germ layers.


It starts with the notochord in vertebrates. 

DB Chapter 1: Introduction

Define "Malformation". 

= abnormalities caused by genetic events (mutations, chromosomal aneuploidies) 

DB Chapter 1: Introduction

Define "Disruption".

Abnormalities caused by exogenous agents (teratogens).

DB Chapter 1: Introduction

What are examples for teratogens

Chemicals, viruses, radiation, ... 

DB Chapter 1: Introduction

What are advantages of the sea urchin as a model organism for study of development? 

- transparent egg and embryo

- synchronous development 

- easily maintainable 

DB Chapter 1: Introduction

What are the main topics of developmental biology?

- Differentiation

- Morphogenesis 

- Growth

- Reproduction

- Regeneration

- Evolution

DB Chapter 1: Introduction

What are advantages for the nematode (caenorhbditis elegans) as a model organism for study of development?

- first animal with sequenced genome 

- transparent 

- development exactly determined

- short generation time 

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