Case Studys Immunology at Fachhochschule Salzburg | Flashcards & Summaries

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Lernmaterialien für case studys immunology an der Fachhochschule Salzburg

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What is typical for typ 1 allergy (hypersensitivity)?
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- immune response towards harmless proteins
- failure of the immune system
- th2-cells play a major role in this disease
- b-cells evolve into igE-producing plasma cells
- igE is normally used to fight parasitic infections
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TESTE DEIN WISSEN
Why do some of us mount an allergic response to a speficic antigen? 
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TESTE DEIN WISSEN
Exact reaseons are still unknown!
- genetic
- hygiene
- enviromental pollution
- diet
Development of allergic reaction is multifactorial
Allergens are structurally diverse
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TESTE DEIN WISSEN
What do you know about nitration?
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TESTE DEIN WISSEN
- can enhance allergic responses
- nitration results in multimerisation of the nitrated proteins (in some cases)
- multimers are known to induce stronger immune responses (example HLA tetramers)
- this might be a mechanism behind the observed effects
- nitration might occur in the lung due to inflammation 
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TESTE DEIN WISSEN
Immunotoxicological effects of nanoparticels?
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TESTE DEIN WISSEN
- cytotoxic and immunotoxic effects can be measured
- shape, surface coating and charge, solubility can affect the cellular responses
- grouping of the materials will allow us to cope with the huge diversity of materials
- translation of the in vivo situation should ne performed

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TESTE DEIN WISSEN
What does immunotoxicology mean? 
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TESTE DEIN WISSEN
determines the effects of external factors on the immune system
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TESTE DEIN WISSEN
For what are models systems and animal models are needed?
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TESTE DEIN WISSEN
To understand the immune responses and evaluate the risk
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TESTE DEIN WISSEN
Understanding of immunotoxicological processes allows us to?
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TESTE DEIN WISSEN
- better understand diseases
- protect peoplefrom harmful agents
- help to generate novel treatment strategies
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TESTE DEIN WISSEN
Lifespam of a sperm & oocyte?
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TESTE DEIN WISSEN
sperm: 5 days
oocyte: 12-24h
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TESTE DEIN WISSEN
What does idiopathie mean? 
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unknown cause
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TESTE DEIN WISSEN
Why can autoimmunity occur regarding sperm?
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TESTE DEIN WISSEN
Testis -> immunopriveleged area
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TESTE DEIN WISSEN
Elimination phase?
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TESTE DEIN WISSEN
Body cells identify tumor cells and start eliminating them
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TESTE DEIN WISSEN
What does „immunotoxicology“ mean?
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TESTE DEIN WISSEN
The study of adverse effects on the immune system resulting directly or indirectly from occupational, enviromental or therapeutic exposure to chemicals (including drugs), biologic materials and, in certain instances, physiological factors, collectively referred to as agents.
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  • 17197 Karteikarten
  • 429 Studierende
  • 6 Lernmaterialien

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Q:
What is typical for typ 1 allergy (hypersensitivity)?
A:
- immune response towards harmless proteins
- failure of the immune system
- th2-cells play a major role in this disease
- b-cells evolve into igE-producing plasma cells
- igE is normally used to fight parasitic infections
Q:
Why do some of us mount an allergic response to a speficic antigen? 
A:
Exact reaseons are still unknown!
- genetic
- hygiene
- enviromental pollution
- diet
Development of allergic reaction is multifactorial
Allergens are structurally diverse
Q:
What do you know about nitration?
A:
- can enhance allergic responses
- nitration results in multimerisation of the nitrated proteins (in some cases)
- multimers are known to induce stronger immune responses (example HLA tetramers)
- this might be a mechanism behind the observed effects
- nitration might occur in the lung due to inflammation 
Q:
Immunotoxicological effects of nanoparticels?
A:
- cytotoxic and immunotoxic effects can be measured
- shape, surface coating and charge, solubility can affect the cellular responses
- grouping of the materials will allow us to cope with the huge diversity of materials
- translation of the in vivo situation should ne performed

Q:
What does immunotoxicology mean? 
A:
determines the effects of external factors on the immune system
Mehr Karteikarten anzeigen
Q:
For what are models systems and animal models are needed?
A:
To understand the immune responses and evaluate the risk
Q:
Understanding of immunotoxicological processes allows us to?
A:
- better understand diseases
- protect peoplefrom harmful agents
- help to generate novel treatment strategies
Q:
Lifespam of a sperm & oocyte?
A:
sperm: 5 days
oocyte: 12-24h
Q:
What does idiopathie mean? 
A:
unknown cause
Q:
Why can autoimmunity occur regarding sperm?
A:
Testis -> immunopriveleged area
Q:
Elimination phase?
A:
Body cells identify tumor cells and start eliminating them
Q:
What does „immunotoxicology“ mean?
A:
The study of adverse effects on the immune system resulting directly or indirectly from occupational, enviromental or therapeutic exposure to chemicals (including drugs), biologic materials and, in certain instances, physiological factors, collectively referred to as agents.
case studys immunology

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